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Accepted for/Published in: JMIR Serious Games

Date Submitted: Feb 26, 2018
Open Peer Review Period: Feb 27, 2018 - May 3, 2018
Date Accepted: Jul 17, 2018
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Digital Gaming to Improve Adherence Among Adolescents and Young Adults Living With HIV: Mixed-Methods Study to Test Feasibility and Acceptability

Castel AD, Qasmieh S, Greenberg D, Ellenberger N, Howell TH, Griffith C, Wilbourn BC, Ganesan K, Hussein N, Ralte G, Rakhmanina N

Digital Gaming to Improve Adherence Among Adolescents and Young Adults Living With HIV: Mixed-Methods Study to Test Feasibility and Acceptability

JMIR Serious Games 2018;6(4):e10213

DOI: 10.2196/10213

PMID: 30322838

PMCID: 6231793

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Digital Gaming to Improve Adherence Among Adolescents and Young Adults Living With HIV: Mixed-Methods Study to Test Feasibility and Acceptability

  • Amanda D Castel; 
  • Saba Qasmieh; 
  • Daniel Greenberg; 
  • Nicole Ellenberger; 
  • Tyriesa Howard Howell; 
  • Caleb Griffith; 
  • Brittany C Wilbourn; 
  • Kavitha Ganesan; 
  • Nadia Hussein; 
  • Gabriel Ralte; 
  • Natella Rakhmanina

Background:

An estimated 50% of adolescents and young adults (AYA) living with HIV are failing to adhere to prescribed antiretroviral treatment (ART). Digital games are effective in chronic disease management; however, research on gaming to improve ART adherence among AYA is limited.

Objective:

We assessed the feasibility and acceptability of video gaming to improve AYA ART adherence.

Methods:

Focus group discussions and surveys were administered to health care providers and AYA aged 13 to 24 years living with HIV at a pediatric HIV program in Washington, DC. During focus group discussions, AYA viewed demonstrations of 3 game prototypes linked to portable Wisepill medication dispensers. Content analysis strategies and thematic coding were used to identify adherence themes and gaming acceptance and feasibility. Likert scale and descriptive statistics were used to summarize response frequencies.

Results:

Providers (n=10) identified common adherence barriers and strategies, including use of gaming analogies to improve AYA ART adherence. Providers supported exploration of digital gaming as an adherence intervention. In 6 focus group discussions, 12 AYA participants identified disclosure of HIV status and irregular daily schedules as major barriers to ART and use of alarms and pillboxes as reminders. Most AYA were very or somewhat likely to use the demonstrated game prototypes to help with ART adherence and desired challenging, individually tailored, user-friendly games with in-game incentives. Game prototypes were modified accordingly.

Conclusions:

AYA and their providers supported the use of digital games for ART adherence support. Individualization and in-game incentives were preferable and informed the design of an interactive technology-based adherence intervention among AYA living with HIV.


 Citation

Please cite as:

Castel AD, Qasmieh S, Greenberg D, Ellenberger N, Howell TH, Griffith C, Wilbourn BC, Ganesan K, Hussein N, Ralte G, Rakhmanina N

Digital Gaming to Improve Adherence Among Adolescents and Young Adults Living With HIV: Mixed-Methods Study to Test Feasibility and Acceptability

JMIR Serious Games 2018;6(4):e10213

DOI: 10.2196/10213

PMID: 30322838

PMCID: 6231793

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.