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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jan 19, 2026
Date Accepted: May 31, 2026

The final, peer-reviewed published version of this preprint can be found here:

Personal Health Large Language Models and the Negotiation of Medical Authority in Clinical Care: Opportunities, Risks, and Governance

Xie W, Liu J, Liu S

Personal Health Large Language Models and the Negotiation of Medical Authority in Clinical Care: Opportunities, Risks, and Governance

J Med Internet Res 2026;28:e91727

DOI: 10.2196/91727

PMID: 42347687

Personal Health LLMs and the Negotiation of Medical Authority in Clinical Care: Opportunities, Risks, and Governance

  • Wenyi Xie; 
  • Jialin Liu; 
  • Siru Liu

ABSTRACT

Personal health large language models (PH-LLMs), exemplified by ChatGPT Health and Fitbit’s Gemini-powered health coach, are emerging consumer-facing systems that synthesize multimodal patient-generated health data into action-oriented narratives, reshaping how patients enter clinical encounters. This shift transforms the traditional dyadic clinician–patient relationship toward an emerging triadic model of negotiated authority in which clinicians must mediate among clinical evidence, patient values, and algorithmic narratives. This paper analyzes how PH-LLMs redistribute epistemic authority and proposes a clinical governance framework to preserve safety, accountability, and trust. Analyzing the intersection of emerging artificial intelligence capabilities and clinical workflows, we identify key opportunities: improved patient participation through structured sensemaking, between-visit support enhancing care continuity, and more collaborative encounters where clinicians function as accountable adjudicators. We also characterize three failure modes: authority conflict when recommendations diverge from clinical judgment, fragmentation of clinical truth across incompatible platforms, and diffusion of accountability across stakeholders. To address these risks, we propose a three-layer governance framework spanning evidence and provenance, clinical arbitration and workflow integration, and competence and accountability. When appropriately governed, PH-LLMs may become enabling infrastructure for safer, person-centered longitudinal care.


 Citation

Please cite as:

Xie W, Liu J, Liu S

Personal Health Large Language Models and the Negotiation of Medical Authority in Clinical Care: Opportunities, Risks, and Governance

J Med Internet Res 2026;28:e91727

DOI: 10.2196/91727

PMID: 42347687

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