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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jan 16, 2026
Date Accepted: Jun 19, 2026

The final, peer-reviewed published version of this preprint can be found here:

Evaluating the Outcomes of the Capacity-Building Support From a Collaborative Network of Implementation Science Technical Assistance Hubs: Protocol for a Mixed Methods Evaluation

Lee SJ, Mestel H, Audet CM, Balasubramanian B, Benbow N, Chandra S, Geremia C, Hernandez-Ramirez RU, Jones J, Keatley O, Kemp C, Khosropour C, Lanzi RG, Millett MLE, Morshed AB, Pettit AC, Powers A, Rabin BA, Sales JM, Stadnick NA, Humphries D

Evaluating the Outcomes of the Capacity-Building Support From a Collaborative Network of Implementation Science Technical Assistance Hubs: Protocol for a Mixed Methods Evaluation

JMIR Res Protoc 2026;15:e91374

DOI: 10.2196/91374

PMID: 42467964

Evaluating the outcomes of the capacity-building support of a collaborative network of implementation science technical assistance hubs: An Evaluation Protocol

  • Sung-Jae Lee; 
  • Hannah Mestel; 
  • Carolyn M Audet; 
  • Bijal Balasubramanian; 
  • Nanette Benbow; 
  • Shruti Chandra; 
  • Carrie Geremia; 
  • Raul U. Hernandez-Ramirez; 
  • Joyce Jones; 
  • Olivia Keatley; 
  • Christopher Kemp; 
  • Christine Khosropour; 
  • Robin Gaines Lanzi; 
  • Mary-Louise E. Millett; 
  • Alexandra B. Morshed; 
  • April C. Pettit; 
  • Alec Powers; 
  • Borsika A. Rabin; 
  • Jessica M. Sales; 
  • Nicole A. Stadnick; 
  • Debbie Humphries

ABSTRACT

Background:

Implementation science (IS) plays a critical role in translating research into real-world health outcomes. Few studies have evaluated models that provide technical assistance (TA) and other resources to build IS capacity. The Coordinating and Capacity-building Hubs to Enhance the Science of HIV Implementation REsearch (CHESHIRE) network supports U.S.-based HIV research awardees participating in the Ending the HIV Epidemic (EHE) initiative.

Objective:

We describe CHESHIRE’s plan to evaluate the impact of hub TA activities on EHE-funded research team outcomes, including IS competencies, scientific collaboration, and research productivity.

Methods:

We will employ qualitative interviews (n=36 EHE-funded research teams), social network analysis (n=265 researchers), and secondary data analysis (NIH RePORTER, PubMed, and NIH ISCI EHE Project Final Progress Report Survey (n=248)) to assess whether CHESHIRE engagement improves researchers’ ability to apply IS frameworks, facilitates inter-institutional partnerships, and enhances scientific output. We will use social network metrics and thematic coding to identify shifts in collaboration and perceived benefits of TA. We will measure productivity by tracking grant submissions, awards, and peer-reviewed publications.

Results:

The findings will provide insight on whether structured IS support through CHESHIRE increases researchers’ self-efficacy, cross-institutional collaboration, and funding/publication success.

Conclusions:

This evaluation will provide empirical evidence to guide the development and optimization of TA hubs in public health research and inform their future evaluation. Findings will inform strategies to optimize IS capacity-building models and accelerate the translation of evidence-based interventions into practice, especially in HIV prevention and treatment. Results will inform future use of similar hub-based models across public health domains addressing complex health challenges. Clinical Trial: N/A


 Citation

Please cite as:

Lee SJ, Mestel H, Audet CM, Balasubramanian B, Benbow N, Chandra S, Geremia C, Hernandez-Ramirez RU, Jones J, Keatley O, Kemp C, Khosropour C, Lanzi RG, Millett MLE, Morshed AB, Pettit AC, Powers A, Rabin BA, Sales JM, Stadnick NA, Humphries D

Evaluating the Outcomes of the Capacity-Building Support From a Collaborative Network of Implementation Science Technical Assistance Hubs: Protocol for a Mixed Methods Evaluation

JMIR Res Protoc 2026;15:e91374

DOI: 10.2196/91374

PMID: 42467964

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