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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jan 5, 2026
Date Accepted: Aug 25, 2026

The final, peer-reviewed published version of this preprint can be found here:

Automated Brief Hospital Course Summarization in Cardiac Surgery Using a Lightweight Large Language Model–Based Framework: Development and Evaluation Study on the Medical Information Mart for Intensive Care-IV

Gao X, Wang Y, Wang Z, Yuan J, Huang S, Zhang X, Sun Z, Xing Y, Liu Y, Wu X, Hu Z, Zhao W

Automated Brief Hospital Course Summarization in Cardiac Surgery Using a Lightweight Large Language Model–Based Framework: Development and Evaluation Study on the Medical Information Mart for Intensive Care-IV

J Med Internet Res 2026;28:e90870

DOI: 10.2196/90870

Automated Brief Hospital Course Summarization in Cardiac Surgery Using a Lightweight Large Language Model Based Framework: Development and Evaluation Study on MIMIC-IV

  • Xiaoyuan Gao; 
  • Yang Wang; 
  • Zixing Wang; 
  • Jing Yuan; 
  • Shengkang Huang; 
  • Xuyao Zhang; 
  • Zhaohong Sun; 
  • Yun Xing; 
  • Yiyang Liu; 
  • Xintong Wu; 
  • Zhan Hu; 
  • Wei Zhao

ABSTRACT

Background:

Physician documentation requirements are a known contributor to clinician burnout, with the manual creation of brief hospital course (BHC) summaries being particularly time-consuming. Automating BHC summarization may mitigate this workload and reduce documentation errors. However, current natural language processing (NLP) methods are often limited to single-document inputs, and large language models (LLMs) face privacy and deployment challenges. Furthermore, existing methods often require manual information extraction and struggle to maintain temporal accuracy.

Objective:

We developed and evaluated LiteMedDoc, a lightweight, locally deployable LLM-based framework to automatically generate BHC summaries without model fine-tuning. Our objective goal was to determine whether clinically useful clinical summaries could be generated under strict privacy and resource constraints, making automated summarization feasible in real-world hospital environments.

Methods:

LiteMedDoc is a modular pipeline built upon an 8-billion-parameter open-source LLM (Llama 3.1). It features three specialized modules: a Static Dynamic Information Hierarchy (SDIH) module to condense multi-source inputs and structure clinical events chronologically; a Similar Document Retrieval-Augmented Generation (SD-RAG) module that retrieves contextually relevant prior case summaries; and a Self-adaptive Feedback Optimization (SFO) module used offline for prompt optimization. All processing was performed locally without any model fine-tuning. We evaluated the framework on a retrospective cohort of 4,538 coronary artery bypass grafting (CABG) surgery cases from the MIMIC-IV database. A held-out test set of 403 cases was used to generate BHC summaries. The model-generated summaries were compared to reference BHCs using eight standard NLP metrics covering lexical overlap (e.g., BLEU-4, ROUGE), semantic similarity (BERTScore, METEOR), and clinical relevance (AlignScore, MEDCON). Additionally, 15 cardiac surgeons conducted a clinical evaluation of a sample of model-generated summaries, rating them on completeness, correctness, readability, conciseness, and global quality using a 5-point Likert scale.

Results:

Without any model training, LiteMedDoc achieved strong performance across individual automated metrics, nearly matching a fine-tuned model and exceeding a 70-billion-parameter model on all metrics. Additionally, in a within-database cross-domain evaluation on lobectomy cases, the framework maintained encouraging performance after prompt adaptation and outperformed both the base model and the CABG-fine-tuned model. Surgeons rated the AI-generated summaries above the prespecified acceptability threshold across all domains (mean scores ≥3.0), specifically praising their structure and conciseness.

Conclusions:

By integrating three specialized modules, the proposed framework offers a practical, locally deployable solution for clinician-in-the-loop BHC draft generation under privacy and resource constraints, and holds promise for improving documentation efficiency and enhancing information continuity during care transitions.


 Citation

Please cite as:

Gao X, Wang Y, Wang Z, Yuan J, Huang S, Zhang X, Sun Z, Xing Y, Liu Y, Wu X, Hu Z, Zhao W

Automated Brief Hospital Course Summarization in Cardiac Surgery Using a Lightweight Large Language Model–Based Framework: Development and Evaluation Study on the Medical Information Mart for Intensive Care-IV

J Med Internet Res 2026;28:e90870

DOI: 10.2196/90870

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