Accepted for/Published in: JMIR Research Protocols
Date Submitted: Dec 10, 2025
Date Accepted: Mar 13, 2026
Feasibility of Establishing Community Living Labs (CoLLabs) to Improve Access to Prostate Health Resources, Education, Amenities & Community Health: Protocol for a Pragmatic Clinical Trial
ABSTRACT
Background:
In 2022, nearly 60,000 prostate cancer (CaP) cases were reported among Black men (BM), who face an estimated lifetime risk of approximately 1 in 6, compared with 1 in 8 among White men (WM). Non-Hispanic BM experience the highest CaP-related mortality rates of any racial or ethnic group in the United States. The disproportionate burden of CaP in BM has been attributed to a combination of health-system factors, variations in care processes, and individual- or patient-level determinants. Addressing these multilevel contributors will require innovative strategies to advance prostate health equity.
Objective:
In this paper, we discuss the protocol for assessing the feasibility of establishing a Community Living Lab (CoLLab) Learning Health System in Black communities and the impact on facilitating access to prostate health Resources, Education, Amenities & Community Health (REACH) services for BM.
Methods:
A mixed-method approach was employed for the study. The methodology was guided by the Intervention Mapping Framework, a framework that provides a systematic and stepwise approach for designing, implementing, and evaluating an intervention, focusing on program design, adoption and implementation and monitoring and evaluation plan. The research setting was Northeast Florida with the intervention based in three American Legion Posts (ALPs) and the control in one ALP. CoLLab REACH services were co-created with community members and provided by Community Health Workers (CHWs). The primary outcomes for the study are: (1) improvement of BM’s CaP awareness, knowledge, attitude, health beliefs, perceived control, intentions and cues to action; and (2) increase in BM’s clinical trials’ awareness, knowledge, attitude, perceived control, intentions and cues to action.
Results:
The CoLLab study received institutional ethics committee approval on March 20, 2024. Baseline recruitment for the intervention arm has been completed, with 195 BM enrolled across intervention ALPs. To date, 11 participants have been enrolled at the control ALP, and recruitment for the control arm remains ongoing. Data analysis will be conducted upon completion of follow-up assessments at Months 6, 10, and 14.
Conclusions:
We successfully co-designed the CoLLab REACH services at three ALPs. CoLLab is a precision community health initiative that delivers timely, culturally responsive prostate health services to Black communities across the CaP care continuum, along with resources addressing social determinants of health (SDOH). Using a pretest–posttest design, we will assess the intervention’s impact at both the individual and community levels to evaluate the feasibility of this community-based, culturally informed approach. In addition, we will examine the feasibility of replicating the CoLLab Learning Health System in Black communities nationwide. Clinical Trial: NCT06541210
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