Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Dec 9, 2025
Date Accepted: Jun 10, 2026

The final, peer-reviewed published version of this preprint can be found here:

A Locally Executable AI System for Improving Preoperative Patient Communication: Multidomain Clinical Evaluation

Sato M, Nagata S, Ohnuma M, Takahashi H, Kakazu T, Yamamura M, Yoshikawa A, Matsushita Y

A Locally Executable AI System for Improving Preoperative Patient Communication: Multidomain Clinical Evaluation

JMIR Med Inform 2026;14:e89173

DOI: 10.2196/89173

PMID: 42478927

A Locally Executable AI System for Improving Preoperative Patient Communication: A Multi-Domain Clinical Evaluation

  • Motoki Sato; 
  • Sou Nagata; 
  • Mizuho Ohnuma; 
  • Hidekazu Takahashi; 
  • Tomoaki Kakazu; 
  • Masayuki Yamamura; 
  • Atsushi Yoshikawa; 
  • Yuki Matsushita

ABSTRACT

Background:

Large language models (LLMs) offer promising capabilities for medical communication but face significant barriers in clinical deployment, including data privacy concerns, the risk of hallucinations, and high energy consumption associated with cloud-based infrastructure. Existing solutions often prioritize performance over sustainability and local implementability.

Objective:

The aim of this study was to develop and evaluate "LENOHA" (Low Energy, No Hallucination, Leave No One Behind Architecture), a locally executable AI system designed to ensure data privacy, prevent hallucinations, and minimize energy consumption while maintaining high conversational accuracy in preoperative settings.

Methods:

We constructed a hybrid system running on a local consumer GPU (NVIDIA RTX 3080). The architecture routes clinical queries to a non-generative FAQ matcher (Sentence Transformer) and casual conversation to a local small language model (SLM). We evaluated the system using expert-supervised synthetic datasets across two domains: tooth extraction and gastroscopy. Performance metrics included classification accuracy, response latency, and power consumption (mWh/request) compared to a generative-only approach.

Results:

The system achieved a classification accuracy of 0.983, which was statistically indistinguishable from GPT-4o. The non-generative clinical path consumed approximately 1.0 mWh per request, whereas the generative path required approximately 168.4 mWh, representing a ~170-fold difference in energy efficiency. The system effectively eliminated hallucinations for clinical queries by design.

Conclusions:

LENOHA demonstrates that a locally executable, hybrid AI architecture can achieve high performance and safety while significantly reducing energy consumption and eliminating data privacy risks. This study provides a sustainable model for deploying medical AI in resource-constrained environments. Clinical Trial: N/A


 Citation

Please cite as:

Sato M, Nagata S, Ohnuma M, Takahashi H, Kakazu T, Yamamura M, Yoshikawa A, Matsushita Y

A Locally Executable AI System for Improving Preoperative Patient Communication: Multidomain Clinical Evaluation

JMIR Med Inform 2026;14:e89173

DOI: 10.2196/89173

PMID: 42478927

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.