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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Oct 23, 2025
Date Accepted: Jun 11, 2026

The final, peer-reviewed published version of this preprint can be found here:

Temporal Trends in Type 2 Diabetes Burden and Care Outcomes in Taiwan From 2012 to 2021: Nationwide Population-Based Cohort Study

Lin MY, Wu YL, Wu HT, Hsu CC, the iH3 Research Group

Temporal Trends in Type 2 Diabetes Burden and Care Outcomes in Taiwan From 2012 to 2021: Nationwide Population-Based Cohort Study

JMIR Public Health Surveill 2026;12:e86356

DOI: 10.2196/86356

PMID: 42636042

Temporal Trends in Type 2 Diabetes Burdens and Care Outcomes in Taiwan (2012–2021)

  • Ming-Yen Lin; 
  • Yi-Ling Wu; 
  • Hsiao-Ting Wu; 
  • Chih-Cheng Hsu; 
  • the iH3 Research Group

ABSTRACT

Background:

Understanding dynamic changes in non-communicable diseases is crucial for informing health policy precisely and improving population-level outcomes.

Objective:

This study analyzed trends in key health metrics to update the care gaps for type 2 diabetes in one high-income country.

Methods:

We conducted a nationwide trend analysis of annual incidence, prevalence, mortality, and life expectancy from 2012 to 2021, the ABC (HbA1c, blood pressure, cholesterol) control metrics from 2015 to 2021, and the complication-specific incidences from 2017 to 2021. The selected health metrics were tested by trend analysis and stratified by age and sex, and standardized to understand disparities in trends.

Results:

The standardized incidence and mortality rates of type 2 diabetes slightly declined by an average of 0.025 and 0.022 per 100 patient-years annually, respectively (p for trend = 0.002 and 0.003). These declines coincided with an average annual increase of 0.51% in the standardized prevalence proportion (p for trend < 0.001). While glycemic and lipid control improved steadily, blood pressure control remained suboptimal, reaching only 35.9% in 2021. All complications examined, except nephropathy, showed heterogeneous decreasing trends between ages. The disparity in life expectancy between people with type 2 diabetes and the general population has narrowed over time, but the gap was still pronounced among younger age groups.

Conclusions:

This nationwide analysis highlights critical care gaps—particularly in blood pressure management, nephropathy prevention, and care for younger individuals with type 2 diabetes. Addressing these deficiencies is urgent for achieving more equitable and effective diabetes care. Clinical Trial: N/A


 Citation

Please cite as:

Lin MY, Wu YL, Wu HT, Hsu CC, the iH3 Research Group

Temporal Trends in Type 2 Diabetes Burden and Care Outcomes in Taiwan From 2012 to 2021: Nationwide Population-Based Cohort Study

JMIR Public Health Surveill 2026;12:e86356

DOI: 10.2196/86356

PMID: 42636042

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