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Accepted for/Published in: Online Journal of Public Health Informatics

Date Submitted: Jul 22, 2025
Date Accepted: Feb 18, 2026
Date Submitted to PubMed: Feb 19, 2026

The final, peer-reviewed published version of this preprint can be found here:

Workflow‑Based Information Management Framework for Multicenter Research Studies: Design and Development

Sulaeman H, Stone M, Bruhn R, Zurita K, Nguyen A, Chiang V, Jones J, Deng X, Custer B, Busch M, Grebe E

Workflow‑Based Information Management Framework for Multicenter Research Studies: Design and Development

Online J Public Health Inform 2026;18:e81119

DOI: 10.2196/81119

PMID: 41712767

Workflow-based Information Management: a nimble, abstracted framework for information management in multicenter research studies

  • Hasan Sulaeman; 
  • Mars Stone; 
  • Roberta Bruhn; 
  • Karla Zurita; 
  • Anh Nguyen; 
  • Vincent Chiang; 
  • Jefferson Jones; 
  • Xutao Deng; 
  • Brian Custer; 
  • Michael Busch; 
  • Eduard Grebe

ABSTRACT

Biological and health research is becoming more data-driven. Institutions, including commercial and research laboratories, generate data faster now than ever before. The increasing rate of data generation, along with the lessons learned from the COVID-19 pandemic, necessitates a nimble and dependable data infrastructure for organizations to be able to quickly execute research studies and provide insights to inform public health policy and practice. In this manuscript, we describe our Workflow-based Information Management (WIM) framework, a research information management system built on the open-source and freely available R programming language and the associated ecosystem of community-developed packages. We demonstrate that the framework can be readily adapted to a wide range of epidemiology studies and research projects.


 Citation

Please cite as:

Sulaeman H, Stone M, Bruhn R, Zurita K, Nguyen A, Chiang V, Jones J, Deng X, Custer B, Busch M, Grebe E

Workflow‑Based Information Management Framework for Multicenter Research Studies: Design and Development

Online J Public Health Inform 2026;18:e81119

DOI: 10.2196/81119

PMID: 41712767

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