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Accepted for/Published in: JMIR Mental Health

Date Submitted: Jun 18, 2025
Date Accepted: Sep 27, 2025
Date Submitted to PubMed: Sep 29, 2025

The final, peer-reviewed published version of this preprint can be found here:

AI Applications in Depression Detection and Diagnosis: Bibliometric and Visual Analysis of Trends and Future Directions

Ren W, Xue X, Liu L, Huang J

AI Applications in Depression Detection and Diagnosis: Bibliometric and Visual Analysis of Trends and Future Directions

JMIR Ment Health 2025;12:e79293

DOI: 10.2196/79293

PMID: 41022381

PMCID: 12590047

A Bibliometric and Visual Analysis of Artificial Intelligence Applications in Depression Detection and Diagnosis: Trends and Future Directions

  • Wenbo Ren; 
  • Xiali Xue; 
  • Lu Liu; 
  • Jiahuan Huang

ABSTRACT

Background:

Depression is a highly prevalent and debilitating mental disorder, yet its diagnosis heavily relies on subjective assessments, leading to challenges in accuracy and consistency. The rapid advancements in Artificial Intelligence (AI) offer promising avenues for more objective and efficient diagnostic approaches. Understanding the evolving landscape of AI applications in depression diagnosis is crucial for guiding future research and clinical translation.

Objective:

Objective:

This study aims to provide a comprehensive bibliometric and visual analysis of the global research trends, intellectual structure, and emerging frontiers in the application of AI for depression detection and diagnosis from 2015 to 2024.

Methods:

Methods:

A systematic literature search was conducted on the Web of Science Core Collection database to identify relevant publications on AI applications in depression diagnosis from January 1, 2015, to December 31, 2024. A total of 2304 articles were retrieved and analyzed using bibliometric software CiteSpace. The analysis encompassed temporal trends, keyword dynamics, author collaboration networks, institutional influence, country contributions, and intellectual foundations through co-citation analysis of journals and references.

Results:

Results:

The field demonstrated an exponential growth in publications and citations, particularly after 2018, reflecting increasing academic and clinical interest. Key thematic shifts were observed from traditional machine learning to advanced deep learning, multimodal fusion, and the integration of objective biomarkers (e.g., EEG, facial expressions). Leading contributors included institutions from China and the United States, with emerging collaborative bridges from countries like Canada and Singapore. The intellectual base is highly interdisciplinary, drawing heavily from computer science, neuroscience, and psychiatry, with a notable surge in engineering and translational research.

Conclusions:

Conclusions:

The integration of AI in depression diagnosis is a rapidly maturing and diversifying field, transitioning from theoretical exploration to clinically relevant applications focusing on objective, data-driven approaches. The identified trends underscore the need for enhanced interdisciplinary and international collaboration, ethical framework development, and a focus on translating technological innovations into accessible and equitable mental health solutions. These findings offer valuable insights for researchers, clinicians, and policymakers to strategically advance AI-assisted depression diagnostics globally. Clinical Trial: Not applicable


 Citation

Please cite as:

Ren W, Xue X, Liu L, Huang J

AI Applications in Depression Detection and Diagnosis: Bibliometric and Visual Analysis of Trends and Future Directions

JMIR Ment Health 2025;12:e79293

DOI: 10.2196/79293

PMID: 41022381

PMCID: 12590047

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