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Accepted for/Published in: JMIR Infodemiology

Date Submitted: Jun 10, 2025
Open Peer Review Period: Jun 23, 2025 - Aug 18, 2025
Date Accepted: Dec 23, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Audience-Specific Health Communication: Mixed Methods Evaluation of the Maria Ciência AI-Assisted Knowledge Translation Tool

Araújo-Pereira M, Villalva-Serra K Jr, Pires-Ramos G, Sousa-Peres B, Conceição-Oliveira JN, Maiche SD, Silva RRdC, Andrade BdB

Audience-Specific Health Communication: Mixed Methods Evaluation of the Maria Ciência AI-Assisted Knowledge Translation Tool

JMIR Infodemiology 2026;6:e78843

DOI: 10.2196/78843

PMID: 41813239

PMCID: 12978924

Maria Ciência: Application of Artificial Intelligence for Audience-Specific Health Communication and Knowledge Dissemination

  • Mariana Araújo-Pereira; 
  • Klauss Villalva-Serra Jr; 
  • Gustavo Pires-Ramos; 
  • Beatriz Sousa-Peres; 
  • Joanã Nascimento Conceição-Oliveira; 
  • Sarah Dourado Maiche; 
  • Rebeca Rebouças da Cunha Silva; 
  • Bruno de Bezerril Andrade

ABSTRACT

Background:

Scientific misinformation remains a major barrier to effective health communication. Bridging the gap between academic research and public understanding requires tools that simplify scientific language and adapt content to diverse audiences.

Objective:

This study presents Maria Ciência, a specialized GPT-based assistant for science communication. The tool supports researchers in translating peer-reviewed scientific findings through simple prompts into accessible, ethically appropriate materials tailored for children, the general public, health professionals, and policymakers.

Methods:

The tool was configured using prompt engineering techniques and guided by curated reference materials on inclusive and non-stigmatizing scientific language. Materials derived from 47 public health articles resulted in 188 outputs, which were assessed by 121 evaluators using four criteria: clarity, level of detail, language suitability, and content quality.

Results:

Globally, mean scores were high: clarity (4.90), language suitability (4.78), content quality (4.72), and level of detail (4.56), on a 5-point scale. Materials for children and the general public consistently achieved the highest ratings across all criteria.

Conclusions:

A targeted comparison with the base large language model (ChatGPT 4o) demonstrated superior performance of Maria Ciência in contextual stability. Maria Ciência demonstrates the potential of AI-assisted tools to enhance knowledge translation and counter scientific misinformation by producing scalable, audience-specific content.


 Citation

Please cite as:

Araújo-Pereira M, Villalva-Serra K Jr, Pires-Ramos G, Sousa-Peres B, Conceição-Oliveira JN, Maiche SD, Silva RRdC, Andrade BdB

Audience-Specific Health Communication: Mixed Methods Evaluation of the Maria Ciência AI-Assisted Knowledge Translation Tool

JMIR Infodemiology 2026;6:e78843

DOI: 10.2196/78843

PMID: 41813239

PMCID: 12978924

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