Accepted for/Published in: Journal of Medical Internet Research
Date Submitted: May 31, 2025
Date Accepted: Dec 31, 2025
A tailored internet-delivered mindfulness-based interventions for patients with hepatocellular carcinoma after TACE: A qualitative Study
ABSTRACT
Background:
Hepatocellular carcinoma (HCC) patients undergoing transarterial chemoembolization (TACE) suffer significant psychological distress, impacting outcomes. While mindfulness-based interventions (MBIs) are beneficial, access is limited. Internet-delivered MBIs (iMBIs) offer an accessible alternative, yet qualitative understanding of patient experiences with tailored iMBIs for this specific population is lacking.
Objective:
This study aimed to explore the facilitators and barriers of HCC patients post-TACE and participated in tailored iMBIs.
Methods:
From November 2020 to December 2022, 11 HCC patients post-TACE who had taken part in tailored iMBIs were purposively recruited from a tertiary hospital in Jilin Province. Data were collected through semi-structured interviews lasting 30 to 60 minutes. The interviews were analyzed using conventional content analysis.
Results:
Five main categories emerged from the analysis: (1)Mindfulness Mindset: including acceptance, calmness, and mood improvement.(2)Improvement of Physical Discomfort: such as better sleep, pain relief, reduced gastrointestinal symptoms, and increased activity levels.(3)Resistance to Mindfulness Practice: including perceived lack of effectiveness, unsuitable conditions, equipment limitations, and difficulty concentrating.(4)Support and Encouragement: involving social support, supervision, and professional guidance.(5)Accessibility and Convenience: characterized by restoration of life balance and user-friendly features of the practice. Each category encompassed several subcategories reflecting the diverse experiences of participants.
Conclusions:
While iMBIs were generally perceived as convenient and accessible, challenges such as equipment limitations were noted. Future implementation should focus on enhancing supportive factors to improve adherence, minimizing barriers, and refining the design and delivery of iMBI programs.
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