JMIR Publications

ABSTRACT

Background:

Pathology reports contain critical information necessary to manage cancer patient care. Efforts to structure pathology cancer reports by the College of American Pathologists and the International Collaboration on Cancer Reporting (ICCR) have been successful in standardizing pathology reports. Likewise, methods to improve data computability and exchange by standards development organizations have progressed to make pathology cancer reports interoperable.

Objective:

This study aims to provide a tractable method to render pathology cancer reports computable and interoperable using published cancer reporting protocols, SNOMED Clinical Terms (SNOMED CT) and Heath Level 7 (HL7) Fast Healthcare Interoperability Resources (FHIR).

Methods:

The ICCR colorectal cancer (CRC) reporting dataset version 1.0 was evaluated by terminologists and pathologists. SNOMED CT concepts were bound to the data elements. The dataset was then converted into a FHIR structured data capture (SDC) questionnaire using the United States National Library of Medicine (US NLM) tooling and rendered into a FHIR conformant message for data exchange.

Results:

The ICCR CRC dataset contained 216 data elements, 207 data elements could be bound to SNOMED CT and incorporated into a FHIR SDC construct. The 9 uncoded data elements were ambiguous and could not be reliably encoded. The resultant FHIR SDC form fully represented the ICCR CRC dataset and rendered these data in a R4 JSON format data exchange.

Conclusions:

This project demonstrates a tractable and extensible approach to make cancer pathology reports fully computable and interoperable that can be broadly adopted. ICCR datasets are supported internationally and supported by multiple national societies of pathology. These datasets are fully represented using SNOMED CT to render data elements computable and semantically faithful to their intended meaning. The use of the FHIR SDC construct enables widespread, common data exchange of clinical information. While challenges of FHIR adoption as well as maintaining currency of clinical content and standard terminology remain, the presented approach provides a clear pathway towards implementation.