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Accepted for/Published in: JMIR Dermatology

Date Submitted: Apr 25, 2025
Date Accepted: Sep 25, 2025

The final, peer-reviewed published version of this preprint can be found here:

Long-Term Efficacy and Safety of755-nm Alexandrite Laser for Axillary Hair Removal: ِA Comparative Analysis of Single vs. DualFlash lamp Systems

Shurrab K, Nassr M

Long-Term Efficacy and Safety of755-nm Alexandrite Laser for Axillary Hair Removal: ِA Comparative Analysis of Single vs. DualFlash lamp Systems

JMIR Dermatol 2025;8:e76523

DOI: 10.2196/76523

PMID: 41270270

PMCID: 12638035

Long-Term Efficacy and Safety of 755 nm Alexandrite Laser for Axillary Hair Removal: A Comparative Analysis of Single vs. Dual Flash Lamp Systems

  • Kawthar Shurrab; 
  • Manal Nassr

ABSTRACT

Background:

Laser hair removal is a non-invasive cosmetic procedure that targets melanin in hair follicles using selective photothermolysis

Objective:

evaluate the long-term effectiveness of 755 nm laser parameters for hair removal by comparing single-flash and dual-flash lamp techniques.

Methods:

Forty women aged 20 to 35 with Fitzpatrick skin types II and III participated in a study on laser hair removal for their axillae. Participants underwent three treatment sessions, each spaced four weeks apart, from January to April 2024. They were divided into two groups, both receiving treatments with an Alexandrite laser (755 nm, 14 mm spot size). The first group was treated with a dose of 8 J/cm² using a single flash lamp device operating at 5 Hz, with a pulse duration of 10 ms. The second group received doses between 9 and 11 J/cm² from a dual flash lamp device operating at 2.5 Hz, with pulse durations ranging from 10 to 15 ms. Photographs and hair counts were taken at baseline and one month after the final session. A T-test assessed statistical significance, and regression analysis evaluated treatment effects. Pain scores and side effects were collected using a Visual Analogue Scale (VAS) in a satisfaction questionnaire.

Results:

The dual flash lamp laser achieved an overall hair reduction of 94%, while the one flash lamp laser resulted in a 91.4% reduction in the axilla. The difference was not statistically significant, with a p-value of 0.143. Both devices had no serious adverse effects reported, indicating effective safety features

Conclusions:

The results show that both techniques provide similar results in terms of efficacy and safety, with no reported side effects and results maintained even after six and twelve months of follow-up.


 Citation

Please cite as:

Shurrab K, Nassr M

Long-Term Efficacy and Safety of755-nm Alexandrite Laser for Axillary Hair Removal: ِA Comparative Analysis of Single vs. DualFlash lamp Systems

JMIR Dermatol 2025;8:e76523

DOI: 10.2196/76523

PMID: 41270270

PMCID: 12638035

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