Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Apr 15, 2025
Date Accepted: Jul 31, 2025

The final, peer-reviewed published version of this preprint can be found here:

Fine-Tuning Methods for Large Language Models in Clinical Medicine by Supervised Fine-Tuning and Direct Preference Optimization: Comparative Evaluation

Savage T, Ma S, Boukil A, Rangan E, Lopez I, Chen J

Fine-Tuning Methods for Large Language Models in Clinical Medicine by Supervised Fine-Tuning and Direct Preference Optimization: Comparative Evaluation

J Med Internet Res 2025;27:e76048

DOI: 10.2196/76048

PMID: 40986888

PMCID: 12457693

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Per the author's request this version is not available.