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Accepted for/Published in: JMIR Aging

Date Submitted: Apr 13, 2025
Date Accepted: Jun 13, 2025

The final, peer-reviewed published version of this preprint can be found here:

The Impact of Social Stress and Healthy Lifestyle on the Mortality of Chinese Older Adults: Prospective Cohort Study

Yang J, Huang J, Huang Q, Gao J, Liu D, Li Z, Lv Y, Shi X, Mao C

The Impact of Social Stress and Healthy Lifestyle on the Mortality of Chinese Older Adults: Prospective Cohort Study

JMIR Aging 2025;8:e75942

DOI: 10.2196/75942

PMID: 40795324

PMCID: 12342692

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

The impact of social stress and healthy lifestyle on the mortality of Chinese older adults: a prospective cohort study

  • Jin Yang; 
  • Jilong Huang; 
  • Qingmei Huang; 
  • Jian Gao; 
  • Dan Liu; 
  • Zhihao Li; 
  • Yuebin Lv; 
  • Xiaoming Shi; 
  • Chen Mao

ABSTRACT

Objectives:This study aimed to investigate the effects of social stress (SS) on older Chinese adults and whether lifestyle factors mediate this association.

Methods:

Three groups of social stress were defined through latent class analysis: low, medium, and high. We created a healthy lifestyle index based on smoking, alcohol consumption, physical activity, and diet.Multivariable Cox proportional hazards models, interaction analyses, and mediation analyses were conducted. Result:Among 27,585 participants above 65years old the hazard ratios for all-cause mortality in the moderate and high SS groups were 1.15 and 1.28, respectively. For individuals aged ≥80 years, the medium SS group had a 28% (HR=1.28, 95% CI: 1.22-1.34) increased mortality risk, and the high SS group had a 38% (HR=1.38, 95% CI: 1.26-1.52) increased risk compared to the low SS group.A healthy lifestyle mediated a small proportion of the association between SS and mortality. Conclusion:A healthy lifestyle only partially mediates the relationship between SS and survival in the elderly, and other effective measures are needed to reduce the risk of death in the elderly.


 Citation

Please cite as:

Yang J, Huang J, Huang Q, Gao J, Liu D, Li Z, Lv Y, Shi X, Mao C

The Impact of Social Stress and Healthy Lifestyle on the Mortality of Chinese Older Adults: Prospective Cohort Study

JMIR Aging 2025;8:e75942

DOI: 10.2196/75942

PMID: 40795324

PMCID: 12342692

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