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Accepted for/Published in: JMIR Formative Research

Date Submitted: Jan 30, 2025
Date Accepted: May 26, 2025

The final, peer-reviewed published version of this preprint can be found here:

Generative AI–Powered Mental Wellness Chatbot for College Student Mental Wellness: Open Trial

Reyes-Portillo J, So A, McAlister K, Nicodemus C, Golden A, Jacobson C, Huberty J

Generative AI–Powered Mental Wellness Chatbot for College Student Mental Wellness: Open Trial

JMIR Form Res 2025;9:e71923

DOI: 10.2196/71923

PMID: 40726405

PMCID: 12303582

Generative Artificial Intelligence Powered Mental Wellness Chatbot for College Student Mental Wellness: An Open Trial

  • Jazmin Reyes-Portillo; 
  • Amy So; 
  • Kelsey McAlister; 
  • Christine Nicodemus; 
  • Ashleigh Golden; 
  • Colleen Jacobson; 
  • Jennifer Huberty

ABSTRACT

Background:

Colleges have turned to digital mental health interventions to meet the increasing mental health treatment needs of their students. Among these, chatbots stand out as artificial intelligence (AI)-driven tools capable of engaging in human-like conversations that have demonstrated some effectiveness in reducing depression and anxiety symptoms.

Objective:

The current study aimed to assess the feasibility and acceptability of using Wayhaven, an AI chatbot among college students with elevated depression and/or anxiety symptoms. We also aimed to examine the preliminary effectiveness of Wayhaven in improving symptoms of anxiety and depression, hopelessness, agency, and self-efficacy among students.

Methods:

Participants were 50 ethnoracially diverse college students with elevated depression and/or anxiety symptoms (80% female, mean age = 22.12 [SD=4.42]). Students were asked to use Wayhaven over the course of one week and completed assessments at pre-intervention, after one session, and one week.

Results:

Wayhaven use was associated with a significant decrease in depression (b= -1.62, P<.001), anxiety (b= -2.15, P<.001), and hopelessness (b= -.64, P<.001) and a significant increase in agency (b= .64, P=0.32), self-efficacy (b= .53, P=.021), and well-being (t=2.90, P<.01, d=.45) across the study period. Most students also reported being satisfied with Wayhaven and it being a tool they would recommend to their peers.

Conclusions:

Findings suggest that Wayhaven may be a viable mental wellness resource for diverse students with elevated depression/anxiety symptoms. Clinical Trial: N/A


 Citation

Please cite as:

Reyes-Portillo J, So A, McAlister K, Nicodemus C, Golden A, Jacobson C, Huberty J

Generative AI–Powered Mental Wellness Chatbot for College Student Mental Wellness: Open Trial

JMIR Form Res 2025;9:e71923

DOI: 10.2196/71923

PMID: 40726405

PMCID: 12303582

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