Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Jan 4, 2025
Open Peer Review Period: Jan 31, 2025 - Mar 28, 2025
Date Accepted: Dec 21, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Distinguishing Common Digital Phenotyping and Self-Report Parameters for Monitoring and Predicting Depression: Scoping Review

Busshart L, Petrovic M, Amin R, Hegerl U

Distinguishing Common Digital Phenotyping and Self-Report Parameters for Monitoring and Predicting Depression: Scoping Review

JMIR Mhealth Uhealth 2026;14:e70840

DOI: 10.2196/70840

PMID: 41773670

PMCID: 12954677

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Distinguishing Common Parameters for Monitoring and Predicting Depression via Digital Tools. A Scoping Review

  • Lisa Busshart; 
  • Milica Petrovic; 
  • Rebeka Amin; 
  • Ulrich Hegerl

ABSTRACT

Background:

Digital health interventions based on self-management strategies aim to empower users’ self-reliance by utilizing self-monitoring, self-assessment and sensor-based output. The existing variety of digital devices utilizes a wide range of data sources and sensors to collect and monitor users’ output while little comparative data on parameter reliability and utility is available.

Objective:

This review aims to address the existing methodological and knowledge gap in understanding the efficient common parameters used among digital health interventions for depression that allow precise monitoring and prediction of the course of depression across different modes of digital intervention delivery.

Methods:

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews digital databases including PubMed, Embase, Cochrane Library and Web of Science Core Collection were scoped for literature ranging from 2021 to 2024. A five-stage framework by Arksey and O’Malley (2005) was implemented to ensure systematic scoping of the literature. The quality of the retrieved studies was assessed using the Downs and Black Instrument and the Mixed Methods Appraisal Tool.

Results:

The overall five interdependent categories were defined including 1) Physical activity and Location, 2) Behavioural patterns, 3) Physiological data, 4) Sleep, and 5) Sociability and Self-reported assessments to best describe common assessment parameters across the literature. Eleven common clinical measures and self-report assessments were distinguished across defined categories as assessment combined with digital phenotyping methodology.

Conclusions:

Synthesis of result sections of the included studies indicated that predicting depressive symptoms by combining clinical assessment and digital phenotyping is a promising approach for further improvement of digital interventions. The overall strongest associations were found in combined approaches using parameters across categories combining sensor data and self-report assessment.


 Citation

Please cite as:

Busshart L, Petrovic M, Amin R, Hegerl U

Distinguishing Common Digital Phenotyping and Self-Report Parameters for Monitoring and Predicting Depression: Scoping Review

JMIR Mhealth Uhealth 2026;14:e70840

DOI: 10.2196/70840

PMID: 41773670

PMCID: 12954677

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.