Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Human Factors

Date Submitted: Jan 7, 2025
Open Peer Review Period: Jan 14, 2025 - Mar 11, 2025
Date Accepted: Nov 25, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Interest in and Predictors of Engagement With a Virtual Reality Intervention Among People With Chronic Pain: Cross-Sectional Survey Study

Bryant GR, Holzman SA, Perez HR

Interest in and Predictors of Engagement With a Virtual Reality Intervention Among People With Chronic Pain: Cross-Sectional Survey Study

JMIR Hum Factors 2026;13:e70598

DOI: 10.2196/70598

PMID: 41672469

PMCID: 12936654

Virtual Reality Intervention for People with Chronic Pain: An Evaluation of Interest In and Predictors Of Treatment Engagement

  • Genevieve R Bryant; 
  • Samuel A Holzman; 
  • Hector R Perez

ABSTRACT

Background:

Although chronic pain (CP) is highly prevalent, current modalities are not sufficient in addressing the needs of people living with this condition. Pharmacological treatments for CP can have severe side effects and increase likelihood of patients overdosing or developing addiction. Behavioral treatments are often indicated for the treatment of CP, but barriers to treatment are common. Virtual reality (VR)-based interventions have shown promise as an effective and potentially accessible form of treatment for CP. However, previous research into VR interventions for people living with CP has not often included diverse populations, including people of racial and ethnic minorities and low socio-economic status.

Objective:

This study sought to gauge interest of patients with chronic pain in participating in a hypothetical study of at-home VR for CP. Patients were recruited from a low socio-economic and racially and ethnically diverse population. Additionally, the study sought to identify predictors of interest in the intervention.

Methods:

42 participants living with CP, recruited from an EMR database, a research participant database, and a pain clinic, completed surveys about demographics, pain levels, technology usage, and knowledge of VR. Bivariate testing was used to determine which, if any, of the above constructs were associated with interest in a hypothetical study of at-home VR for CP. Participants also answered an open-ended question about interest in participating in a VR intervention for CP, that were coded using a thematic analysis framework.

Results:

Despite low technology use and little knowledge and experience with VR, results showed high interest among patients in participating in a hypothetical study of at-home VR for CP. More frequent email usage and using Facebook predicted being somewhat or very interested in participating in a VR clinical trial for pain. Majority of participants cited interest due to the novelty of VR, followed by desperation for pain relief.

Conclusions:

Contrary to a comprehensive body of evidence, we did not find attitudinal barriers to participating in a clinical trial of VR. While we found that use of technology and knowledge of VR was low, interest in a virtual reality intervention for CP was high. Future, fully powered studies should seek to confirm the effectiveness of VR treatments for people with CP, especially those from lower socio-economic, and racially/ethnically diverse backgrounds.


 Citation

Please cite as:

Bryant GR, Holzman SA, Perez HR

Interest in and Predictors of Engagement With a Virtual Reality Intervention Among People With Chronic Pain: Cross-Sectional Survey Study

JMIR Hum Factors 2026;13:e70598

DOI: 10.2196/70598

PMID: 41672469

PMCID: 12936654

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.