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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Dec 5, 2024
Date Accepted: Sep 1, 2025

The final, peer-reviewed published version of this preprint can be found here:

Comparison of Virus Watch COVID-19 Positivity, Incidence, and Hospitalization Rates With Other Surveillance Systems: Surveillance Study

Fong WLE, Nguyen VG, Beale S, Byrne TE, Geismar C, Fragaszy E, Kovar J, Yavlinsky A, Abubakar I, Hayward AC, Aldridge RW

Comparison of Virus Watch COVID-19 Positivity, Incidence, and Hospitalization Rates With Other Surveillance Systems: Surveillance Study

JMIR Public Health Surveill 2025;11:e69655

DOI: 10.2196/69655

PMID: 41021969

PMCID: 12479050

Comparison of Virus Watch COVID-19 positivity, incidence and hospitalisation rates with other surveillance systems: Surveillance Study

  • Wing Lam Erica Fong; 
  • Vincent Grigori Nguyen; 
  • Sarah Beale; 
  • Thomas E Byrne; 
  • Cyril Geismar; 
  • Ellen Fragaszy; 
  • Jana Kovar; 
  • Alexei Yavlinsky; 
  • Ibrahim Abubakar; 
  • Andrew C Hayward; 
  • Robert W Aldridge

ABSTRACT

Background:

Effective disease surveillance is essential for understanding epidemiology, detecting outbreaks, and enabling timely public health responses, as demonstrated during the COVID-19 pandemic. In the UK, large-scale studies such as the ONS COVID-19 Infection Survey (CIS) monitored SARS-CoV-2 transmission but required significant resources, making them challenging to sustain in resource-limited settings. In contrast, the Virus Watch study, with a lower cost, relied on self-reported data and symptomatic testing, while SARI Watch leveraged hospital data for cost-effective surveillance.

Objective:

Our study evaluates Virus Watch’s effectiveness in tracking COVID-19 trends, using ONS CIS and SARI Watch as benchmarks for comparison.

Methods:

We used the Virus Watch prospective community cohort study to estimate COVID-19 positivity, incidence and hospitalisation rates in England and Wales from June 2020 to February 2023. We compared our findings with modelled positivity and incidence rates from ONS CIS and COVID-19 hospitalisation rates from SARI Watch using 9-week rolling Spearman’s ⍴ correlation to measure synchrony.

Results:

58,628 participants were recruited into the Virus Watch study between June 2020 and March 2022, of whom 52,526 (90%) were reported to be living in England and 1,532 (2.6%) in Wales. Virus Watch estimates of COVID-19 positivity and incidence rates in England and Wales were highly correlated with those from ONS CIS. Despite lower absolute values in Virus Watch estimates, both studies showed strong global (overall ⍴s > 0.90) and local (median ⍴s > 0.75) synchrony over time. However, Virus Watch estimates of hospitalisations with COVID-19 were significantly lower and less synchronised with SARI Watch estimates (overall: 0.72, P<.001; median: 0.49, IQR 0.15-0.70). In Wales, Virus Watch estimates exhibited greater variability and lower local synchrony compared to England (overall positivity ⍴: 0.75, P<.001; overall incidence rate ⍴: 0.85, P<.001).

Conclusions:

Our results highlight the effectiveness of the Virus Watch approach in providing accurate estimates of COVID-19 positivity and incidence rates, even in the absence of national surveillance systems. This low-cost method can be adapted to various settings, particularly low-resource ones, to strengthen public health surveillance and inform timely interventions.


 Citation

Please cite as:

Fong WLE, Nguyen VG, Beale S, Byrne TE, Geismar C, Fragaszy E, Kovar J, Yavlinsky A, Abubakar I, Hayward AC, Aldridge RW

Comparison of Virus Watch COVID-19 Positivity, Incidence, and Hospitalization Rates With Other Surveillance Systems: Surveillance Study

JMIR Public Health Surveill 2025;11:e69655

DOI: 10.2196/69655

PMID: 41021969

PMCID: 12479050

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© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.