Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Nov 29, 2024
Date Accepted: Mar 20, 2025

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

Seiterö A, Henriksson P, Thomas K, Henriksson H, Löf M, Bendtsen M, Müssener U

Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

J Med Internet Res 2025;27:e69425

DOI: 10.2196/69425

PMID: 40262133

PMCID: 12056421

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effectiveness of a Mobile Phone Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

  • Anna Seiterö; 
  • Pontus Henriksson; 
  • Kristin Thomas; 
  • Hanna Henriksson; 
  • Marie Löf; 
  • Marcus Bendtsen; 
  • Ulrika Müssener

ABSTRACT

Background:

Although mobile phone-based interventions (mHealth) have demonstrated effectiveness in modifying one or two health risk behaviors at a time, there is a knowledge gap regarding the effects of stand-alone mHealth interventions on multiple health risk behaviors.

Objective:

To estimate the effectiveness of an mHealth intervention (LIFE4YOUth) targeting alcohol, diet, physical activity, and smoking among Swedish high school students.

Methods:

A 2-arm parallel group, single-blind randomized controlled trial (1:1) was conducted from 2020 to 2023 to estimate the 2- and 4-month effectiveness of LIFE4YOUth compared with a waiting-list control group on high school students’ health risk behaviors. Paper and digital advertisement were used to recruit students from high schools in Sweden, covering north, middle and southern areas. Students (n = 756) aged 15-20 years (mean 17.1, SD 1.2; 69% females, 31% males) who met the eligibility criteria of not adhering to ≥1 of 6 guidelines related to the outcomes were included in the trial. All participants received a hyperlink to general health information. The intervention group additionally had 4-month access to LIFE4YOUth: a fully automated intervention including recurring screening, text message services, and an online interactive dashboard. Effects were estimated through self-reported data on weekly alcohol consumption, heavy episodic drinking, fruit and vegetables consumption, sugary drinks consumption, moderate to vigorous physical activity, and smoking cessation.

Results:

In total, 69% and 54% responded to the 2- and 4-month follow-up survey. The intention-to-treat analysis showed similar results from imputed and complete case data. At 2 months, the between-group differences were 0.32 portions/day of fruit and vegetable consumption (95% CI = 0.13; 0.53, probability of effect = 99.9%, P=.001), 50 min/week of physical activity (95% CI = -0.19; 99.73, probability of effect = 97.4%, P=.05), and an incidence rate ratio for heavy episodic drinking of 0.77 (95% CI = 0.55; 1.07, probability of effect = 93.6%, P=.14). At 4 months, a remaining effect was observed on physical activity only. There was no evidence of an effect on smoking. Fifty-eight percent (n = 219) of participants in the intervention group engaged with the LIFE4YOUth intervention at least once.

Conclusions:

The LIFE4YOUth intervention had a modest short-term effect primarily on physical activity and fruit and vegetable consumption. Our results align with previous research on mHealth, suggesting that a multiple behavior approach shows potential in addressing physical inactivity and unhealthy diets, but may not effectively influence adolescents’ alcohol consumption and smoking behaviors.

Conclusions:

The LIFE4YOUth intervention had a modest short-term effect primarily on physical activity and fruit and vegetable consumption. Our results align with previous research on mHealth, suggesting that a multiple behavior approach shows potential in addressing physical inactivity and unhealthy diets, but may not effectively influence adolescents’ alcohol consumption and smoking behaviors. Clinical Trial: ISRCTN (ISRCTN34468623)


 Citation

Please cite as:

Seiterö A, Henriksson P, Thomas K, Henriksson H, Löf M, Bendtsen M, Müssener U

Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial

J Med Internet Res 2025;27:e69425

DOI: 10.2196/69425

PMID: 40262133

PMCID: 12056421

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.