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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Dec 18, 2024
Date Accepted: Aug 5, 2025

The final, peer-reviewed published version of this preprint can be found here:

Potential of the World Health Organization’s Skin NTDs App to Support and Improve the Detection of Skin-Related Neglected Tropical Diseases: Protocol for a Performance Evaluation and Feasibility Study in Senegal

Sall D, Jockers D, Dioussé P, Wachinger J, Batista G, Ruiz Postigo JA, Petitfour L, Robert C, Diallo BM, Faye FA, Dieng Y, Neuerer M, Lawson ATDD, Schwermann F, Carrion C, Zoubi LH, Diagne PM, Kasang C, Sy FNO, Cisse M, Bärnighausen T, Diop M

Potential of the World Health Organization’s Skin NTDs App to Support and Improve the Detection of Skin-Related Neglected Tropical Diseases: Protocol for a Performance Evaluation and Feasibility Study in Senegal

JMIR Res Protoc 2025;14:e69420

DOI: 10.2196/69420

PMID: 40971863

PMCID: 12495362

Potential of the WHO Skin NTDs App to support and improve the detection of skin Neglected Tropical Diseases (NTDs): Protocol for a performance evaluation and feasibility study in Senegal

  • Dior Sall; 
  • Dominik Jockers; 
  • Pauline Dioussé; 
  • Jonas Wachinger; 
  • Gilbert Batista; 
  • Jose Antonio Ruiz Postigo; 
  • Laurene Petitfour; 
  • Charlotte Robert; 
  • Bachir Mansour Diallo; 
  • Fulgence Abdou Faye; 
  • Yacine Dieng; 
  • Maresa Neuerer; 
  • Agbogbenkou Tevi Dela-Dem Lawson; 
  • Felicitas Schwermann; 
  • Carme Carrion; 
  • Louis Hyacinthe Zoubi; 
  • Papa Mamadou Diagne; 
  • Christa Kasang; 
  • Fatou Ndiaye Oumar Sy; 
  • Mahamath Cisse; 
  • Till Bärnighausen; 
  • Madoky Diop

ABSTRACT

Background:

The WHO roadmap aims to control, eliminate or eradicate neglected tropical diseases (NTDs) by promoting innovation in prevention, diagnosis and treatment. In this context, mobile health (mHealth) tools could play an important role to improve health care globally, particularly for skin NTDs. One such tool is the WHO Skin NTDs App (currently available in its beta version), which utilizes AI algorithms to classify skin lesion images and offers diagnostic suggestions and management information to aid primary care personnel in early detection. However, to harness the full potential of this and similar mHealth tools, additional insights into their diagnostic performance and potential implementation avenues in settings with limited access to trained dermatologists are essential.

Objective:

The objective of our mixed-methods study is to test the functionality, operability and potential of the WHO Skin NTDs App (beta version) to support the detection of skin NTDs and common skin conditions at the community level in Senegal.

Methods:

To test the performance of the WHO Skin NTDs App, we will compare the diagnosis suggested by the AI algorithm to a reference diagnosis established by dermatologists at the Thiès regional hospital in Senegal. Our target sample size are 800 skin lesion images. For the qualitative component, we will conduct in-depth interviews with national and international stakeholders (policy makers, community leaders, healthcare providers, software developers) to explore the general usefulness and potential of the application in the Senegalese context and to prepare an app-based intervention to be piloted in this setting.

Results:

We expect the results to provide detailed insights into the feasibility and potential of the WHO Skin NTDs App to support and improve the detection of skin NTDs and common skin conditions at the community level in Senegal. We started data collection in August 2024, with the first results expected to be available in early 2025.

Conclusions:

Our study will assess the performance and potential use of the WHO Skin NTDs App to detect skin NTDs and common skin conditions in Senegal, outlining its potential role in supporting early diagnoses and enhancing public health responses. Clinical Trial: DRKS-ID: DRKS00034297


 Citation

Please cite as:

Sall D, Jockers D, Dioussé P, Wachinger J, Batista G, Ruiz Postigo JA, Petitfour L, Robert C, Diallo BM, Faye FA, Dieng Y, Neuerer M, Lawson ATDD, Schwermann F, Carrion C, Zoubi LH, Diagne PM, Kasang C, Sy FNO, Cisse M, Bärnighausen T, Diop M

Potential of the World Health Organization’s Skin NTDs App to Support and Improve the Detection of Skin-Related Neglected Tropical Diseases: Protocol for a Performance Evaluation and Feasibility Study in Senegal

JMIR Res Protoc 2025;14:e69420

DOI: 10.2196/69420

PMID: 40971863

PMCID: 12495362

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