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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Nov 21, 2024
Date Accepted: Jun 19, 2025

The final, peer-reviewed published version of this preprint can be found here:

Lifestyle eHealth and mHealth Interventions for Children and Adolescents: Systematic Umbrella Review and Meta–Meta-Analysis

Singh B, Ahmed M, Staiano AE, Vasiloglou MF, Gough C, Petersen JM, Yin Z, Vandelanotte C, Kracht C, Fiedler J, Timm I, Dallinga J, Sivakumar B, Baumann H, Huong C, Wunsch K, Suárez-Reyes M, Schoeppe S, Button AM, Spring K, Maher C

Lifestyle eHealth and mHealth Interventions for Children and Adolescents: Systematic Umbrella Review and Meta–Meta-Analysis

J Med Internet Res 2025;27:e69065

DOI: 10.2196/69065

PMID: 41106821

PMCID: 12579299

Lifestyle e- and m-health interventions for children and adolescents: a systematic umbrella review and meta-meta-analysis.

  • Ben Singh; 
  • Mavra Ahmed; 
  • Amanda E. Staiano; 
  • Maria F. Vasiloglou; 
  • Claire Gough; 
  • Jasmine M. Petersen; 
  • Zenong Yin; 
  • Corneel Vandelanotte; 
  • Chelsea Kracht; 
  • Janis Fiedler; 
  • Irina Timm; 
  • Joan Dallinga; 
  • Bridve Sivakumar; 
  • Hannes Baumann; 
  • Christopher Huong; 
  • Kathrin Wunsch; 
  • Mónica Suárez-Reyes; 
  • Stephanie Schoeppe; 
  • Alyssa M. Button; 
  • Katherine Spring; 
  • Carol Maher

ABSTRACT

Background:

Electronic and mobile health (e- and m-health) interventions show promise in promoting healthy behaviours among children and adolescents.

Objective:

The aim of this systematic umbrella review and meta-meta-analysis was to evaluate the effectiveness of e- and m-health interventions in promoting healthy behaviours among children and adolescents.

Methods:

Nine databases were searched for systematic reviews and meta-analyses of randomised controlled trials (RCTs) of e- and m-health interventions targeting physical activity, sedentary behaviour, sleep, and dietary outcomes in children and adolescents were eligible. Screening and data extraction, and all assessments were completed by two reviewers. Study quality was assessed using the AMSTAR-2 tool, and meta-analyses were conducted to combine effect sizes using random effects models. Subgroup analyses examined participant and intervention characteristics.

Results:

Twenty-five systematic reviews comprising 440 RCTs and 133,501 participants, mostly involving healthy children and adolescents (n=18) or those with overweight/obesity (n=4) were included. Interventions mostly included active video games or serious games (n=8), various m-health (n=6), various e-health (n=5), combined e- and m-health (n=4), wearables (n=1), and computer-based interventions (n=1) and most had a critically low AMSTAR-2 score (n=18). Meta-analyses based on standardised mean difference (SMD) showed significant effects (all p<0.05) for moderate-to-vigorous physical activity (MVPA, SMD=0.18 [95% CI=0.09, 0.27]), total physical activity (SMD=0.24 [95% CI= 0.13, 0.35]), fat intake (SMD=0.10 [95% CI= 0.02, 0.18]), fruit and vegetable intake (SMD=0.11 [95% CI= 0.00, 0.22]), body mass index (BMI) (SMD=0.19 [95% CI=0.11, 0.27]), and body weight (SMD=0.15 [95% CI=0.01, 0.30]). No effects were found for sedentary behaviour (SMD=0.12 [95% CI=-0.11, 0.35]) or sleep (SMD=0.27 [95% CI=-0.09, 0.63]). Shorter interventions (<8 weeks) had a greater effect on MVPA than longer interventions (≥8 weeks), while longer interventions (≥12 weeks) had a greater effect on BMI compared with shorter interventions.

Conclusions:

E- and m-health interventions offer modest but meaningful improvements in physical activity, diet, and weight management in children and adolescents, with important implications for integrating digital tools into health promotion strategies. Clinical Trial: The protocol was preregistered on PROSPERO (ID: CRD42024537019)


 Citation

Please cite as:

Singh B, Ahmed M, Staiano AE, Vasiloglou MF, Gough C, Petersen JM, Yin Z, Vandelanotte C, Kracht C, Fiedler J, Timm I, Dallinga J, Sivakumar B, Baumann H, Huong C, Wunsch K, Suárez-Reyes M, Schoeppe S, Button AM, Spring K, Maher C

Lifestyle eHealth and mHealth Interventions for Children and Adolescents: Systematic Umbrella Review and Meta–Meta-Analysis

J Med Internet Res 2025;27:e69065

DOI: 10.2196/69065

PMID: 41106821

PMCID: 12579299

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