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Accepted for/Published in: JMIR Aging

Date Submitted: Nov 6, 2024
Date Accepted: Mar 5, 2025

The final, peer-reviewed published version of this preprint can be found here:

Edentulousness and the Likelihood of Becoming a Centenarian: Longitudinal Observational Study

Wei X, Zhuang L, Li Y, Shi J, Yang Y, Lai H, Liu B

Edentulousness and the Likelihood of Becoming a Centenarian: Longitudinal Observational Study

JMIR Aging 2025;8:e68444

DOI: 10.2196/68444

PMID: 40116785

PMCID: 11951808

Edentulousness reduces the likelihood of becoming a centenarian: longitudinal observational study

  • Xindi Wei; 
  • Longfei Zhuang; 
  • Yuan Li; 
  • Junyu Shi; 
  • Yijie Yang; 
  • Hongchang Lai; 
  • Beilei Liu

ABSTRACT

Background:

In recent decades, global life expectancy has risen notably to approximately 73.5 years worldwide, coinciding with a rapid growth in the elderly population, which presents a significant public health challenge in promoting healthy aging and longevity.

Objective:

This study aimed to prospectively investigate the link between edentulousness and the likelihood of reaching centenarian status among individuals aged 80 years and older.

Methods:

Data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) were analyzed. Logistic regression models were employed to assess the relationship between edentulousness and the likelihood of becoming a centenarian. Demographic characteristics, lifestyle habits, and disease histories were adjusted as confounding factors. Several sensitivity analyses, including the propensity score matching (PSM) and 2-year lag analysis were conducted to further assess the association between edentulousness and becoming a centenarian. The correlation between natural teeth number as a continuous variable and becoming a centenarian was evaluated as well.

Results:

The study included 4,239 participants aged 80 to 100 years. After adjusting for all covariates, the likelihood for becoming a centenarian increased in the non-edentulous group compared to the edentulous group (OR=1.384, 95%CI 1.093-1.751). The relationship persisted after PSM analyses (OR=1.272, 95%CI 1.037-1.561). The association remained statistically significant after excluding participants with a follow-up duration of less than 2 years (OR=1.522, 95%CI 1.083-2.140). Furthermore, a significant positive association between the number of natural teeth and becoming a centenarian was found after adjusting all covariates (OR=1.022, 95%CI 1.002-1.042), which aligned with the main results of the study.

Conclusions:

The findings revealed that the presence of natural teeth was linked to an increased probability of becoming centenarians, underscoring the importance of maintaining oral health even in advanced age.


 Citation

Please cite as:

Wei X, Zhuang L, Li Y, Shi J, Yang Y, Lai H, Liu B

Edentulousness and the Likelihood of Becoming a Centenarian: Longitudinal Observational Study

JMIR Aging 2025;8:e68444

DOI: 10.2196/68444

PMID: 40116785

PMCID: 11951808

Per the author's request the PDF is not available.

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