Accepted for/Published in: JMIR Rehabilitation and Assistive Technologies
Date Submitted: Nov 1, 2024
Date Accepted: Apr 17, 2025
Effectiveness of robot-assisted upper extremity function training (Gloreha®) on upper extremities function after stroke: Systematic review
ABSTRACT
Background:
The Gloreha® is a robotic device that enhances conventional rehabilitation for improving upper extremity function after stroke, but comprehensive evidence on its effectiveness is still lacking.
Objective:
The objective of this study is to evaluate the effectiveness of the Gloreha® device on upper extremity function and activities of daily living (ADLs) in stroke patients.
Methods:
PubMed, Cochrane CENTRAL, CINAHL, EMBASE, and EBSCO open dissertation was searched from 2013 to January 2024. The inclusion criteria were randomized controlled trials (RCT) involving adult stroke patients that compared rehabilitation with the Gloreha® device to conventional rehabilitation and reported upper extremity function or ADLs outcomes. All included studies underwent bias risk assessment using the Revised Cochrane risk-of-bias tool for randomized trials.
Results:
Out of 1,123 studies identified, three RCTs involving 86 participants were included. Of these, two trials combined Gloreha® training with conventional rehabilitation while in another trial, patients engaged solely in the training by Gloreha® device. The Gloreha® whether integrated with conventional rehabilitation or used independently, has the potential to enhance motor function and functional ability in stroke survivors.
Conclusions:
Gloreha® passive training with conventional rehabilitation improves upper extremity function post-stroke, but ADL effects and long-term optimal dosing require further research. Clinical Trial: CRD42024509492
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