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Accepted for/Published in: JMIR Aging

Date Submitted: Sep 12, 2024
Open Peer Review Period: Sep 27, 2024 - Nov 22, 2024
Date Accepted: Jun 3, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of Iso-Inertial Resistance Training on Muscle Power in Middle-Older Adults: Randomized Controlled Trial

Cadellans Arroniz A, Romero Rodríguez D, Zárate Lozano V, Dantony F, Madruga Parera M, Ortega Cebrian S, Blanco D

Effectiveness of Iso-Inertial Resistance Training on Muscle Power in Middle-Older Adults: Randomized Controlled Trial

JMIR Aging 2025;8:e66414

DOI: 10.2196/66414

PMID: 40840466

PMCID: 12370268

Effectiveness of iso-inertial resistance training on muscle power in middle-older adults: a randomised controlled trial

  • Aïda Cadellans Arroniz; 
  • Daniel Romero Rodríguez; 
  • Víctor Zárate Lozano; 
  • Flora Dantony; 
  • Marc Madruga Parera; 
  • Silvia Ortega Cebrian; 
  • David Blanco

ABSTRACT

Background:

Resistance training is used to prevent the decrease in muscle strength associated with age.

Objective:

This study evaluates the effectiveness of iso-inertial training on power, physical performance, and risk of falls compared to gravitational training in physically active middle-older adults.

Methods:

Parallel-group, randomised controlled trial at Espai Esport Wellness Center (Granollers, Spain). Forty-four physically active adults (age >57) were randomised to iso-inertial (n=21) or gravitational (n=23) training groups (R software; 1:1 ratio). Participants had to complete a 6-week training program (2 sessions/week) consisting of three exercises (forward and side lunge, forward lunge with row). Primary outcome: power in the eccentric phase of each exercise evaluated with both iso-inertial and gravitational devices. Secondary outcomes: concentric power, physical performance, risk of falls. Only outcome evaluators were blinded. We used multivariate linear regression models for the analysis.

Results:

27 participants completed the program (n=15 iso-inertial, n=12 gravitational). Iso-inertial training showed better eccentric power gains than gravitational training for the iso-inertial system evaluation, although the difference was only statistically significant for the side lunge. Forward lunge: between-group difference 4.50 W (95% CI: -2.94 to 11.94, p=0.23); side lunge: difference 9.24 W (95% CI: 2.99 to 15.49; p=0.00); forward lunge with row: difference 15.25 W (95% CI: -0.63 -to 31.13, p=0.06). We observed no differences for the gravitational system evaluation nor for concentric power, physical performance, and risk of falls. The two groups improved remarkably from baseline for all outcomes.

Conclusions:

Iso-inertial training leads to better eccentric power gains than gravitational training and therefore could be considered by clinicians when prescribing resistance training to middle-older adults. Both training systems were equally effective in improving concentric power and physical performance, and reducing risk of falls. Clinical Trial: This study was registered at Clinicaltrials.gov (NCT06160089).


 Citation

Please cite as:

Cadellans Arroniz A, Romero Rodríguez D, Zárate Lozano V, Dantony F, Madruga Parera M, Ortega Cebrian S, Blanco D

Effectiveness of Iso-Inertial Resistance Training on Muscle Power in Middle-Older Adults: Randomized Controlled Trial

JMIR Aging 2025;8:e66414

DOI: 10.2196/66414

PMID: 40840466

PMCID: 12370268

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