JMIR Publications

ABSTRACT

Background:

A clinic-based National Diabetes Prevention Program (NDPP) tailored to Black and Latino men has the potential to address prior limitations of NDPP implementation and reduce gender-based diabetes disparities.

Objective:

This study was designed to 1) Assess the effect of Power-Up (a men-centered virtual NDPP program) vs. standard care, mixed-gender virtual NDPP on percent weight loss among racial and ethnic minority men at risk for diabetes; 2) Compare engagement of racial and ethnic minority men at risk for diabetes in Power-Up vs. standard care NDPP; and 3) Evaluate the reach, effectiveness, adoption, implementation, and costs of Power-Up. We hypothesize that men randomized to Power-Up will achieve significantly greater weight loss (% weight loss from baseline) at 16-weeks and 1-year than men randomized to the standard, mixed-gender NDPP group. Men randomized to Power-Up will also have significantly greater engagement and retention than men randomized to the standard care NDPP.

Methods:

Using the electronic health record (EHR) systems of a large academic medical center and a network of small to medium independent primary care practices throughout New York City, we identified Black and Latino men that meet the eligibility criteria for NDPP.

Results:

We enrolled 301 participants through our health system partners. Men were randomized 1:1 to either the Power-Up intervention arm or to a standard, mixed-gender NDPP.

Conclusions:

This manuscript describes the Power-Up trial design and allocation of participants to NDPP groups. Clinical Trial: ClinicalTrials.gov NCT04104243