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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: May 11, 2024
Open Peer Review Period: May 17, 2024 - Jul 12, 2024
Date Accepted: Dec 9, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Virtual Reality Interventions and Chronic Pain: Scoping Review

Ding ME, Traiba H, Perez HR

Virtual Reality Interventions and Chronic Pain: Scoping Review

J Med Internet Res 2025;27:e59922

DOI: 10.2196/59922

PMID: 39965778

PMCID: 11888090

Virtual Reality Interventions and Chronic Pain: A Scoping Review

  • Michael Edward Ding; 
  • Hajar Traiba; 
  • Hector R Perez

ABSTRACT

Background:

Virtual Reality (VR) interventions have demonstrated efficacy for more than a decade for mood and anxiety disorders, and emerging evidence suggests they can reduce pain symptoms in both acute and chronic pain. More recently these interventions have abounded within the commercial and academic sector, immersing participants within a virtual environment to confer health benefits to users. Immersion produced through VR can facilitate delivery of health interventions by isolating participants from distractors and stressors in a therapeutic environment. While recent studies of VR interventions have exploded, they not been uniform in approach or device type, limiting generalizability. Recent scoping reviews on VR and chronic pain have focused on specific diseases or limited inquiries to specific interventions or study types.

Objective:

The objective of our scoping review was to generate new knowledge about the sum total of VR studies in chronic pain with specific emphasis on the methods and results of each study, including (1) the type of interventions, (2) outcomes chosen, (3) samples studied, and (4) data generated.

Methods:

A scoping review was performed of the literature on virtual reality and chronic pain to describe themes associated with the literature to date and identify important gaps and unanswered questions to guide future research. CINAHL and Pubmed were queried for terms “virtual reality” and “pain”, providing studies of chronic pain adult participants using VR delivered through headset displays. A descriptive–analytical method was used to extract data, compare studies, and contextualize the presented outcomes. Articles were categorized into several themes including type of intervention, outcomes chosen, participant characteristics, degree to which immersion was achieved and adverse effect monitoring and reporting.

Results:

A total of 36 articles were included in our analysis. We summarize the literature using five themes: 1) heterogeneity of chronic pain types, 2) highly variable intervention types, 3) highly variable secondary and exploratory outcomes, 4) immersion was highly variable between studies and not systemically explored in many articles, and 5) side effect monitoring was limited.

Conclusions:

We found that the literature on VR in chronic pain is highly variable and lacks theoretical rigor. While there is emerging evidence that supports VR use in a wide variety of health conditions including chronic pain, future research should focus on producing theoretically rigorous work that focuses on mechanisms and that systematically assesses side effects in order to generate robust generalizable knowledge.


 Citation

Please cite as:

Ding ME, Traiba H, Perez HR

Virtual Reality Interventions and Chronic Pain: Scoping Review

J Med Internet Res 2025;27:e59922

DOI: 10.2196/59922

PMID: 39965778

PMCID: 11888090

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