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Accepted for/Published in: JMIR XR and Spatial Computing (JMXR)

Date Submitted: Mar 25, 2024
Date Accepted: Dec 6, 2024

The final, peer-reviewed published version of this preprint can be found here:

At-Home Virtual Reality Intervention for Patients With Chronic Musculoskeletal Pain: Single-Case Experimental Design Study

Slatman S, Heesink L, Achterkamp R, Broeks J, Monteiro de Oliveira N, ter Riet R, Stegeman M, Tabak M

At-Home Virtual Reality Intervention for Patients With Chronic Musculoskeletal Pain: Single-Case Experimental Design Study

JMIR XR Spatial Comput 2025;2:e58784

DOI: 10.2196/58784

PMCID: 12671306

At-home virtual reality intervention for patients with chronic musculoskeletal pain: a single-case experimental design study

  • Syl Slatman; 
  • Lieke Heesink; 
  • Reinoud Achterkamp; 
  • José Broeks; 
  • Nelson Monteiro de Oliveira; 
  • Remko ter Riet; 
  • Marjolein Stegeman; 
  • Monique Tabak

ABSTRACT

Background:

Virtual reality (VR) could possibly alleviate complaints related to chronic musculoskeletal pain (CMP), however little is known about how it affects pain-related variables on an individual level and how patients experience this intervention.

Objective:

This study aimed to gain detailed insight in the influence of an at-home VR intervention for pain education and management on pain-related variables, and to explore its feasibility and general experience.

Methods:

The study applied a single-case experimental design (ABA) in which an at-home VR intervention was used for four weeks by patients with CMP who were on a waiting list for regular pain treatment. Outcome measures included pain-related variables, functioning, and objectively measured outcomes (i.e. stress, sleep, steps). Outcomes were analyzed using data visualization (based on line plots) and statistical methods (i.e. Tau-U and reliable change index) on an individual and group level. In addition, a focus group was conducted to assess feasibility and general experience, to substantiate findings from the SCED study. This focus group was analyzed using inductive thematic analysis.

Results:

Seven participants (six females (86%)) with a median age of 45 (range: 31-61) participated in this study. A dataset with 42 measurement moments was collected with a median of 280 (range: 241-315) data points per participant. No statistically significant or clinically relevant differences between the intervention and no-intervention phases were found. Results of the visual analysis of the diary data showed that patients responded differently to the intervention. Results of the focus group with 3 participants showed that the VR intervention was perceived as a feasible and valued additional intervention.

Conclusions:

Although patients expressed a positive perspective on this VR intervention, it did not seem to influence pain-related outcomes. Individual patients responded differently to the intervention, which implies that this intervention might not be suitable for all patients. Future studies should examine for which patients with CMP VR is effective and explore its working mechanisms. Also, future larger trials should be conducted to complement this study’s findings on the effectiveness of this intervention for patients with CMP and whether VR prevents deterioration on the waiting list compared to a control group.


 Citation

Please cite as:

Slatman S, Heesink L, Achterkamp R, Broeks J, Monteiro de Oliveira N, ter Riet R, Stegeman M, Tabak M

At-Home Virtual Reality Intervention for Patients With Chronic Musculoskeletal Pain: Single-Case Experimental Design Study

JMIR XR Spatial Comput 2025;2:e58784

DOI: 10.2196/58784

PMCID: 12671306

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