Accepted for/Published in: JMIR Bioinformatics and Biotechnology
Date Submitted: Mar 15, 2024
Date Accepted: Aug 18, 2024
Internet-based abnormal chromosomal diagnosis during pregnancy: A non-invasive innovative approach to detecting chromosomal abnormalities in fetus
ABSTRACT
Background:
Chromosomal abnormalities are genetic disorders caused by chromosome errors, leading to developmental delays, birth defects, and miscarriages. Currently, invasive procedures like amniocentesis or chorionic villus sampling are mostly used, which carry a risk of miscarriage. This has led to the need for a non-invasive and innovative approach to detect and prevent chromosomal abnormalities during pregnancy.
Objective:
This review aims to describe and appraise the potential of internet-based abnormal chromosomal preventive measures as a non-invasive approach to detecting and preventing chromosomal abnormalities during pregnancy.
Methods:
A thorough review of existing literature and research on chromosomal abnormalities and non-invasive approaches to prenatal diagnosis and therapy was conducted. Electronic databases such as PubMed, Google Scholar, and ScienceDirect, CENTRAL, CINAHL, Embase, OVID MEDLINE, OVID PsycINFO, Scopus, ACM, and IEEE Xplore were searched for relevant studies and articles published in the last five years. The keywords used included 'chromosomal abnormalities,' 'prenatal diagnosis,' 'non-invasive,' 'internet-based,' and 'therapy.'
Results:
The review of literature revealed that internet-based abnormal chromosomal therapy is a potential non-invasive approach to detecting and preventing chromosomal abnormalities during pregnancy. This innovative approach involves the use of advanced technology, including high-resolution ultrasound, cell-free DNA testing, and bioinformatics, to analyze fetal DNA from maternal blood samples. It allows for early detection of chromosomal abnormalities, enabling timely interventions and treatment to prevent adverse outcomes.
Conclusions:
Internet-based abnormal chromosomal therapy has the potential to revolutionize prenatal care by offering a safe and non-invasive alternative to invasive procedures. It has the potential to improve the detection and prevention of chromosomal abnormalities, leading to better pregnancy outcomes and reduced risk of miscarriage. Further research and development in this field are needed to make this approach more accessible and affordable for pregnant women
Citation
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.