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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Mar 1, 2024
Date Accepted: Dec 18, 2024

The final, peer-reviewed published version of this preprint can be found here:

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

Rampioni M, Leonzi S, Antognoli L, Mura A, Stara V

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

J Med Internet Res 2025;27:e57957

DOI: 10.2196/57957

PMID: 40053744

PMCID: 11920654

Post-Stroke e-Health Technologies-Based Rehabilitation for the Upper Limb Recovery: A Systematic Review of Systematic Reviews

  • Margherita Rampioni; 
  • Sara Leonzi; 
  • Luca Antognoli; 
  • Anna Mura; 
  • Vera Stara

ABSTRACT

Background:

Stroke is one of the most common cerebral vascular diseases, usually affecting people aged 60 and over, leading to a variety of disabilities requiring motor and cognitive rehabilitation. Post-stroke rehabilitation has a lead role in the recovery of the patients, and it is never too late to start. It should be implemented in a structured approach to help patients regain their physical, cognitive, and functional abilities. Technological solutions offer a beneficial and effective alternative to conventional therapy, making rehabilitation more accessible.

Objective:

This study maps and synthesizes the evidence from published systematic reviews that assessed the effectiveness of technology-based rehabilitation for the recovery of the upper limb in post-stroke individuals.

Methods:

Separate literature searches were conducted in PubMed, Web of Science, Scopus and Embase databases and Google Scholar. The PICOS was used to define inclusion criteria. There was no restriction on publication dates. The PRISMA flowchart was used in the retrieval and selection process. Then, the final articles were appraised for their methodological quality using the AMSTAR 2.

Results:

After the search process that identified 1450 records from the 4 databases and an additional 342 by Google Scholar, seven systematic reviews were included. The seven studies were published between 2019 and 2023.

Conclusions:

This review indicated that the field of technology-based rehabilitation is still fragmented due to poor evidence of efficacy. This is probably due to the high heterogeneity of the experimental studies. When developing a technology-based rehabilitation program, it is crucial to carefully plan and link all relevant actors, user-driven design guidelines, and principles of neuroscience. There is a need for further research to understand better the impact of technology interventions on stroke deficits and recovery-related outcomes, both alone and in combination with traditional rehabilitation. This field of research could benefit from standardized rehabilitation protocols provided to patients, enabling comparison and interpretation to discover evidence currently missing.


 Citation

Please cite as:

Rampioni M, Leonzi S, Antognoli L, Mura A, Stara V

Poststroke eHealth Technologies–Based Rehabilitation for Upper Limb Recovery: Systematic Review

J Med Internet Res 2025;27:e57957

DOI: 10.2196/57957

PMID: 40053744

PMCID: 11920654

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