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Accepted for/Published in: JMIR Formative Research

Date Submitted: Feb 21, 2024
Date Accepted: Sep 6, 2024

The final, peer-reviewed published version of this preprint can be found here:

The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study

Epperson N, Davis R, Dempsey A, Haller H, Kupfer DJ, Love T, Martinez P, Matthews M, Moore SL, Muller K, Schneck CD, Scott JL, Zane RD, Frank E

The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study

JMIR Form Res 2025;9:e57624

DOI: 10.2196/57624

PMID: 39773396

PMCID: 11751643

The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study

  • Neill Epperson; 
  • Rachel Davis; 
  • Allison Dempsey; 
  • Heinrich Haller; 
  • David J Kupfer; 
  • Tiffany Love; 
  • Pamela Martinez; 
  • Mark Matthews; 
  • Susan L Moore; 
  • Kimberly Muller; 
  • Christopher D Schneck; 
  • Jessica L Scott; 
  • Richard D Zane; 
  • Ellen Frank

ABSTRACT

Background:

Rhythms, from the company Health Rhythms, is a smartphone platform that uses passively acquired smartphone data and artificial intelligence/predictive analytics to alert patients and providers to an emerging mental health crisis.

Objective:

Our group embedded Rhythms into the electronic health record (EHR) of a large health system, set appropriate alerts based upon passively collected data and patient self-ratings, and tested feasibility and acceptability of Rhythms among patients attending an academic psychiatric outpatient clinic.

Methods:

Patients with a diagnosis of major depressive disorder (MDD), bipolar disorder or other mood disorder were contacted online and enrolled for a 6-week trial of Rhythms. Emergent and urgent alerts were monitored and managed.

Results:

Of the 104 participants, 89 (85.6%) completed six weeks of monitoring. Participants were majority female identifying (72 persons; 69.2%), White (84 persons; 80.8%), non-Hispanic (100 persons; 96.2%) and with diagnosis of MDD (71 persons; 68.3%). Two emergent alerts and 19 urgent alerts were received and managed according to protocol over 16 weeks. Two-thirds of those participating continued to use Rhythms after study completion. Comments from participants indicated appreciation for greater self-awareness and provider connection, while providers reported that Rhythms provided a more nuanced understanding of patient experience between clinical visits.

Conclusions:

Rhythms is a user-friendly, EHR adaptable smartphone-based tool that provides patients and providers with a greater understanding of patient mental health status.


 Citation

Please cite as:

Epperson N, Davis R, Dempsey A, Haller H, Kupfer DJ, Love T, Martinez P, Matthews M, Moore SL, Muller K, Schneck CD, Scott JL, Zane RD, Frank E

The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study

JMIR Form Res 2025;9:e57624

DOI: 10.2196/57624

PMID: 39773396

PMCID: 11751643

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