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Accepted for/Published in: JMIR Diabetes

Date Submitted: Feb 19, 2024
Date Accepted: Dec 9, 2024

The final, peer-reviewed published version of this preprint can be found here:

Diabetes Medical Group Visits and Type 2 Diabetes Outcomes: Mediation Analysis of Diabetes Distress

Reichert M, De La Cruz B, Mitchell S, Gardiner P

Diabetes Medical Group Visits and Type 2 Diabetes Outcomes: Mediation Analysis of Diabetes Distress

JMIR Diabetes 2025;10:e57526

DOI: 10.2196/57526

PMID: 39916354

PMCID: 11825897

Diabetes Medical Group Visits and Type 2 Diabetes Outcomes: A Mediation Analysis of Diabetes Distress

  • Matthew Reichert; 
  • Barbara De La Cruz; 
  • Suzanne Mitchell; 
  • Paula Gardiner

ABSTRACT

Background:

Group-based diabetes care, both technology-enabled and in-person, can improve diabetes outcomes in low-income minority women, but the mechanism remains unclear.

Objective:

We tested whether diabetes medical group visits (DMGVs) reduced hemoglobin A1c (A1c) by mitigating diabetes distress, an emotional response affecting nearly half of adults with type 2 diabetes in community settings.

Methods:

We conducted a mediation and moderation analysis of data from the Women in Control 2.0 (WIC2) comparative effectiveness study, which showed that both technology-enabled and in-person DMGVs improve A1c. We tested whether diabetes distress mediated the relationship between DMGV engagement and reductions in A1c. We also tested whether this relationship was moderated by depressive symptoms and social support. Participants were 309 low-income and minority women. DMGV engagement was measured using the Group Climate questionnaire (GCQ-S). The mediator, diabetes distress, was measured using the Diabetes Distress Scale (DDS-17). The outcome was the 6-month change in A1c (A1c). Social support was measured using the Medical Outcomes Study Social Support Survey.

Results:

Diabetes distress mediated the relationship between engagement and 6-month A1c. Specifically, group engagement affected A1c by reducing distress associated with the emotional burden of diabetes (P = 0.09) and the regimen of diabetes self-management (P = 0.04). The relationship between engagement and 6-month A1c was moderated by depressive symptoms (P = 0.02), and social support (P = 0.08).

Conclusions:

Engagement in DMGVs improved A1c because it helped reduce diabetes-related distress, especially related to the regimen of diabetes management and its emotional burden, and especially for women without depressive symptoms and who lacked social support. Clinical Trial: ClinicalTrials.gov NCT02726425; https://clinicaltrials.gov/ct2/show/NCT02726425


 Citation

Please cite as:

Reichert M, De La Cruz B, Mitchell S, Gardiner P

Diabetes Medical Group Visits and Type 2 Diabetes Outcomes: Mediation Analysis of Diabetes Distress

JMIR Diabetes 2025;10:e57526

DOI: 10.2196/57526

PMID: 39916354

PMCID: 11825897

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