Accepted for/Published in: JMIR Research Protocols
Date Submitted: Aug 22, 2023
Date Accepted: Dec 28, 2023
Simultaneous cardiopulmonary exercise testing and echocardiography for investigation of cardiopulmonary dysfunction in outpatients: a scoping review protocol
ABSTRACT
Background:
Cardiopulmonary dysfunction is a complex process with a broad range of aetiologies. Investigations performed either at rest and/or that only assess function of a single organ (heart or lungs) are often insufficient. Simultaneous cardiopulmonary exercise testing and stress echocardiography (CPET-SE) is a new approach in assessing cardiopulmonary dysfunction as it provides anatomical and functional imaging simultaneously whilst under increasing stress. To date the application of CPET-SE has been broad and without structure, and its effect on patient outcomes is unclear.
Objective:
The objective of this scoping review is to explore and analyse the evidence regarding the role of simultaneous CPET-SE in investigating cardiopulmonary dysfunction in outpatients. It will include any published study in which adult (≥ 18 years) patients have completed a CPET-SE for investigation of cardiopulmonary dysfunction.
Methods:
This review will follow the Arksey and O’Malley framework, supported by the JBI methodology for scoping reviews. It will utilise the PRISMA-ScR checklist. Data sources will include MEDLINE, Scopus, Embase and Cochrane (including reviews, trials and protocols) electronic databases, with no date range defined. The search will be limited to English language with no restrictions regarding pathology. Secondary references of the included sources will also be assessed by a hand search for suitability. A 2 person title-abstract screen and data charting process will be used. Independent experts will be used for consultation including an academic librarian and clinicians. The Covidence software will be used for article screening.
Results:
This scoping review will provide a unified and detailed description of the applications of CPET-SE in investigating cardiopulmonary dysfunction. This will provide a platform for future research harnessing this investigatory method. The results will be presented in both tabular and graphical format to ensure clarity. Results of this scoping review will be submitted to a relevant peer-reviewed academic journal for publication.
Conclusions:
N/A Clinical Trial: This scoping review has been registered on the Open Science Framework (https://osf.io/98r3e).
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Copyright
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