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Accepted for/Published in: JMIR Research Protocols

Date Submitted: May 15, 2023
Date Accepted: Jul 7, 2023

The final, peer-reviewed published version of this preprint can be found here:

Identifying the Characteristics of Responders and Nonresponders in a Behavioral Intervention to Increase Physical Activity Among Patients With Moderate to Severe Asthma: Protocol for a Prospective Pragmatic Study

de Lima FF, Lunardi AC, Pinheiro DHA, Carvalho-Pinto RM, Stelmach R, Giavina‑Bianchi P, Agondi RC, Carvalho C

Identifying the Characteristics of Responders and Nonresponders in a Behavioral Intervention to Increase Physical Activity Among Patients With Moderate to Severe Asthma: Protocol for a Prospective Pragmatic Study

JMIR Res Protoc 2023;12:e49032

DOI: 10.2196/49032

PMID: 37651174

PMCID: 10502597

Identifying the characteristics of responders and non-responders in a behavioral intervention to increase physical activity in patients with moderate to severe asthma: a study protocol

  • Fabiano Francisco de Lima; 
  • Adriana Claudia Lunardi; 
  • David Halen Araújo Pinheiro; 
  • Regina Maria Carvalho-Pinto; 
  • Rafael Stelmach; 
  • Pedro Giavina‑Bianchi; 
  • Rosana Câmara Agondi; 
  • Celso Carvalho

ABSTRACT

Introduction: Previous research has suggested that most adults improve their asthma control after a short-term behavioral intervention program to increase physical activity in daily life (PADL). However, the characteristics of individuals who did not respond to this intervention and the medium-term response remain unknown. Therefore, the study aims will be as follows: i) identify the characteristics of adult responders and non-responders with asthma to a behavioral intervention to increase physical activity and ii) evaluate the functional and clinical benefits in the medium-term.

Methods:

This prospective cohort study will include adults with moderate-to-severe asthma submitted to a behavioral intervention. All individuals will receive an educational program and an eight-week intervention to increase PADL (1x/week; up to 90 min/session). Behavioral intervention will be based on individual feedback aimed at increasing participation in physical activity. Pre- and post-intervention assessments will include the following: PADL (triaxial accelerometry), body composition (octopolar bioimpedance), barriers to PADL (questionnaire), clinical asthma control (asthma control questionnaire-ACQ), quality of life (asthma quality of life questionnaire-AQLQ), anxiety and depression levels (hospital anxiety and depression scale-HADS), and exacerbations. "Responders" to the intervention will be defined as those who demonstrate an increase in the number of daily steps (≥2.500). Discussion: Identifying individuals who respond or do not respond to behavioral interventions to increase PADL will help guide clinicians in prescribing specific interventions to adults with asthma.


 Citation

Please cite as:

de Lima FF, Lunardi AC, Pinheiro DHA, Carvalho-Pinto RM, Stelmach R, Giavina‑Bianchi P, Agondi RC, Carvalho C

Identifying the Characteristics of Responders and Nonresponders in a Behavioral Intervention to Increase Physical Activity Among Patients With Moderate to Severe Asthma: Protocol for a Prospective Pragmatic Study

JMIR Res Protoc 2023;12:e49032

DOI: 10.2196/49032

PMID: 37651174

PMCID: 10502597

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