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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Mar 9, 2023
Open Peer Review Period: Mar 9, 2023 - May 4, 2023
Date Accepted: Mar 11, 2024
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Giving a Voice to Patients With Smell Disorders Associated With COVID-19: Cross-Sectional Longitudinal Analysis Using Natural Language Processing of Self-Reports

Menger NS, Tognetti A, Farruggia MC, Mucignat C, Bhutani S, Cooper KW, Rohlfs Dominguez P, Heinbockel T, Shields V, D'Errico A, Pereda-Loth V, Koyama S, Croijmans I

Giving a Voice to Patients With Smell Disorders Associated With COVID-19: Cross-Sectional Longitudinal Analysis Using Natural Language Processing of Self-Reports

JMIR Public Health Surveill 2024;10:e47064

DOI: 10.2196/47064

PMID: 38728069

PMCID: 11127136

Giving a voice to adults with COVID-19: An analysis of open-ended comments from smell longhaulers and non-longhaulers

  • Nick S. Menger; 
  • Arnaud Tognetti; 
  • Michael C. Farruggia; 
  • Carla Mucignat; 
  • Surabhi Bhutani; 
  • Keiland W. Cooper; 
  • Paloma Rohlfs Dominguez; 
  • Thomas Heinbockel; 
  • Vonnie Shields; 
  • Anna D'Errico; 
  • Veronica Pereda-Loth; 
  • Sachiko Koyama; 
  • Ilja Croijmans

ABSTRACT

Background:

Smell disorders are commonly reported with COVID-19 infection. Some patients show prolonged smell-related issues, even after the respiratory symptoms are resolved. To explore the concerns of patients, and to provide an overview for each specific smell disorder, we explored a longitudinal survey that was administered online, and contained self-reports on the changes of smell that participants (n=1560) experienced at two time points.

Objective:

Participants who still suffered from smell disorders at the second time point, hence named ‘longhaulers’, were compared to those who were not, hence named ‘non-longhaulers’.

Methods:

Specifically, three aims were pursued in this study. First, to classify smell disorders based on the participants’ self-reports. Second, to classify the sentiment of each self-report using a machine learning approach, and third, to find specific keywords that best describe the smell dysfunction in those self-reports.

Results:

We found that the prevalence of parosmia and hyposmia was higher in longhaulers than in non-longhaulers. Furthermore, the results suggest that longhaulers stated self-reports with more negative sentiment than non-longhaulers. Finally, we found specific keywords that were more typical for either longhaulers compared to non-longhaulers.

Conclusions:

Taken together, our work shows consistent findings with previous studies, while at the same time, provides new insights for future studies investigating smell disorders.


 Citation

Please cite as:

Menger NS, Tognetti A, Farruggia MC, Mucignat C, Bhutani S, Cooper KW, Rohlfs Dominguez P, Heinbockel T, Shields V, D'Errico A, Pereda-Loth V, Koyama S, Croijmans I

Giving a Voice to Patients With Smell Disorders Associated With COVID-19: Cross-Sectional Longitudinal Analysis Using Natural Language Processing of Self-Reports

JMIR Public Health Surveill 2024;10:e47064

DOI: 10.2196/47064

PMID: 38728069

PMCID: 11127136

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