Accepted for/Published in: JMIR Diabetes
Date Submitted: Nov 14, 2022
Open Peer Review Period: Nov 14, 2022 - Nov 21, 2022
Date Accepted: Feb 3, 2023
Date Submitted to PubMed: Feb 7, 2023
(closed for review but you can still tweet)
Effectiveness of Insulia® App in French Patients with Type 2 Diabetes Mellitus treated with Basal Insulin. A Longitudinal Observational Study
ABSTRACT
Background:
For patients with Type 2 diabetes (T2DM), calculating daily dose of their basal insulin may be challenging. INSULIA® is a digital remote monitoring solution that uses clinical algorithms to recommend basal insulin doses.
Objective:
Our study was designed to assess the clinical impact of this device in real-life setting.
Methods:
retrospective observational analysis of data collected through the device in adult French patients with T2DM treated with basal insulin ± oral antihyperglycemic agents using the system since at least 6 months was conducted.
Results:
Of the 484 users, 373 (77.0%) performed at least one dose calculation. 59.2% were men. When they started to use the app, mean age, BMI, HbA1c, and basal insulin dose were respectively: 55.8 years (SD: 11.9), 30.6 kg/m2 (SD: 5.9), 10.1% (SD: 2.0) and 25.5 IU/day (SD: 15.8). Over a median duration of use of 5.0 [3.8-5.7] months, patients have used the system 5.8 times/week (SD 1.6) on average and 73.4% of their injected doses were consistent with the doses suggested by the app. Among regular and compliant user patients (n=91, ≥5 measurements/week and ≥80% adherence to calculated doses), 60.4% achieved the FBG target (±5%) at 6 months while the incidence of reported hypoglycaemia has decreased (-0.16%/month). Among 82 patients for whom measures were available, mean HbA1c decreased from 9.9% to 7.2% at 6 months.
Conclusions:
In real life, an improvement in glycaemic control without increasing hypoglycaemic risk is observed in patients regularly using the INSULIA® application and following the dose recommendations of the algorithm. Clinical Trial: NA
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