Accepted for/Published in: Journal of Medical Internet Research
Date Submitted: Oct 12, 2022
Date Accepted: Mar 10, 2023
Efficacy of a mobile phone-based intervention on health behaviors and HIV/AIDS treatment management: a Randomized Controlled Trial
ABSTRACT
Background:
In addition to clinical care for patients with HIV/AIDS, advances in web and mobile technologies hold potentials in supporting treatment management.
Objective:
This study aimed to evaluate the feasibility and efficacy of a theory-based m-health intervention on health behaviors and HIV treatment adherence among patients with HIV/AIDS in Vietnam.
Methods:
A randomized controlled trial was conducted. Both groups received regular consultations with doctors and participate at baseline, 1-month, and 3-month follow-up periods. Patients in the intervention group received a theory-driven smartphone application to facilitate medication adherence and self-efficacy in HIV patients. A total of 428 HIV patients, including 243 patients in the intervention arm and 187 patients in the control arm. To determine the effect of the intervention, we conducted analyses to test a primary hypothesis related to participants between the intervention group and control group about the higher Visual Analog Scale of ART Adherence, HIV treatment adherence self-efficacy scale, and HIV Symptom Management Self-Efficacy Scale.
Results:
In the intervention group, the adherence score increased significantly (Coef. = 1.07; 95% CI: 0.24; 1.90) after 1 month, while the HIV adherence self-efficacy was significantly higher after 3 months (Coef. =2.17; 95% CI: 2.07; 2.27) compared to the control group. The intervention did not influence the change of substance use.
Conclusions:
Our study demonstrated that the m-health application could improve overall antiretroviral treatment adherence self-efficacy of the patients. Further studies with larger sample sizes and longer follow-up periods are needed to support our findings. Clinical Trial: The research has been reviewed and approved by TCTR Committee on 28 September 2022 (Code number is TCTR20220928003).
Citation
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Copyright
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