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Accepted for/Published in: JMIR Mental Health

Date Submitted: Oct 1, 2022
Date Accepted: Feb 13, 2023

The final, peer-reviewed published version of this preprint can be found here:

Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial

Cochran A, Maronge JM, Victory A, Hoel S, McInnis MG, Thomas EB

Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial

JMIR Ment Health 2023;10:e43164

DOI: 10.2196/43164

PMID: 37079363

PMCID: 10160940

Mobile Acceptance and Commitment Therapy in Bipolar Disorder: A Micro-Randomized Trial

  • Amy Cochran; 
  • Jacob M. Maronge; 
  • Amanda Victory; 
  • Sydney Hoel; 
  • Melvin G McInnis; 
  • Emily BK Thomas

ABSTRACT

Background:

Mobile interventions promise to fill in gaps in care with their broad reach and flexible delivery.

Objective:

Our goal was to investigate delivery of a mobile version of Acceptance and Commitment Therapy (ACT) for individuals with bipolar disorder (BP).

Methods:

Individuals with BP (n = 30) participated in a 6-week micro-randomized trial. Twice daily, participants logged symptoms in-app and were repeatedly randomized to receive an ACT intervention or not. Self-reported behavior and mood were measured as the energy devoted to moving toward valued domains or away from difficult emotions and with depressive d and manic m scores from the digital survey of mood in BP survey (digiBP).

Results:

Participants completed an average 66% of in-app assessments. Interventions did not significantly impact average toward energy or away energy but did significantly increase the average manic score m (P = .008) and depressive score d (P = .02). This was driven by increased fidgeting and irritability and interventions focused on increasing awareness of internal experiences.

Conclusions:

Findings do not support a larger study on mobile ACT in BP, but have significant implications for future studies seeking mobile therapy for individuals with BP. Clinical Trial: NCT04098497


 Citation

Please cite as:

Cochran A, Maronge JM, Victory A, Hoel S, McInnis MG, Thomas EB

Mobile Acceptance and Commitment Therapy in Bipolar Disorder: Microrandomized Trial

JMIR Ment Health 2023;10:e43164

DOI: 10.2196/43164

PMID: 37079363

PMCID: 10160940

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