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Accepted for/Published in: JMIR Diabetes

Date Submitted: Sep 12, 2022
Date Accepted: May 24, 2023
Date Submitted to PubMed: Jun 14, 2023

The final, peer-reviewed published version of this preprint can be found here:

Glycemic Control, Renal Progression, and Use of Telemedicine Phone Consultations Among Japanese Patients With Type 2 Diabetes Mellitus During the COVID-19 Pandemic: Retrospective Cohort Study

Sankoda A, Nagae Y, Waki K, Sze WT, Oba K, Mieno M, Nangaku M, Yamauchi T, Ohe K

Glycemic Control, Renal Progression, and Use of Telemedicine Phone Consultations Among Japanese Patients With Type 2 Diabetes Mellitus During the COVID-19 Pandemic: Retrospective Cohort Study

JMIR Diabetes 2023;8:e42607

DOI: 10.2196/42607

PMID: 37315193

PMCID: 10698649

Glycemic control, renal progression, and usage of telemedicine phone consultations among Japanese type 2 diabetes mellitus patients during the COVID-19 pandemic: a retrospective cohort study

  • Akiko Sankoda; 
  • Yugo Nagae; 
  • Kayo Waki; 
  • Wei Thing Sze; 
  • Koji Oba; 
  • Makiko Mieno; 
  • Masaomi Nangaku; 
  • Toshimasa Yamauchi; 
  • Kazuhiko Ohe

ABSTRACT

Background:

Reduced or delayed medical follow-ups has been reported during the COVID-19 pandemic, which may lead to worsening clinical outcomes for diabetes patients. The Japanese government granted special permission for medical institutions to use telephone consultations and other remote communication modes during the COVID-19 pandemic.

Objective:

We aimed to evaluate changes in the frequency of outpatient consultations, glycemic control, and renal function of type 2 DM patients before and during the COVID-19 pandemic.

Methods:

This is a retrospective single center cohort study in Tokyo, Japan, analyzing results for 3035 patients who visited the hospital regularly. We compared the frequency of outpatient consultations attended (both in person and via telemedicine phone consultation), Glycated Hemoglobin A (HbA1c), and estimated Glomerular Filtration Rate (eGFR) among type 2 DM patients during the six months from April 2020 to September 2020 (during the COVID-19 pandemic) with those during the same period of the previous year, 2019 using Wilcoxon signed rank test. We conducted a multivariate logistic regression analysis to identify factors related to the changes in glycemic control and eGFR. We also compared the changes in HbA1c and eGFR from 2019 to 2020 among telemedicine users and telemedicine non-users using Difference-in-Differences design.

Results:

The number of outpatient consultations attended decreased significantly from 3 (2-3) in 2019 to 2 (2-3) in 2020 (P<.001). Median HbA1c levels deteriorated, though not to a clinically significant degree. The rate of decline in eGFR increased. Changes in HbA1c and eGFR did not differ between patients who utilized telemedicine phone consultations and those who did not.

Conclusions:

The COVID-19 pandemic led to declines in the attendance of outpatient consultations among type 2 DM patients, and these patients also encounter deterioration in kidney function. Difference in consultation modality (in person or by phone) did not affect glycemic control and renal progression of the patients.


 Citation

Please cite as:

Sankoda A, Nagae Y, Waki K, Sze WT, Oba K, Mieno M, Nangaku M, Yamauchi T, Ohe K

Glycemic Control, Renal Progression, and Use of Telemedicine Phone Consultations Among Japanese Patients With Type 2 Diabetes Mellitus During the COVID-19 Pandemic: Retrospective Cohort Study

JMIR Diabetes 2023;8:e42607

DOI: 10.2196/42607

PMID: 37315193

PMCID: 10698649

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