Accepted for/Published in: JMIR Research Protocols
Date Submitted: Apr 23, 2022
Date Accepted: May 31, 2022
Effectiveness of Neurodynamic Interventions in Patients with Stroke: A Systematic Review and Meta-Analysis Protocol
ABSTRACT
Background:
Stroke is the most common and serious neurological condition which leads to death, limited functionality and reduced quality of life. Studies with conflicting results and various methodological limitations have been conducted to assess the effectiveness of neurodynamic interventions for patients with stroke.
Objective:
This systematic review and meta-analysis aimed to investigate the pooled effectiveness of different neurodynamic interventions on stroke patients.
Methods:
PubMed, PEDro and Google Scholar databases will be searched for studies published with full text in English language from inception to date. RCTs evaluating the effect of different neurodynamic techniques on patients with stroke will be included. The primary outcome measures will include pain, disability/function and quality of life. Secondary outcome measures will include physical performance measures such as balance, range of motion, muscle strength, specific diagnostic and neurodynamic test outcomes. The screening, data extraction and methodological quality assessment will be performed by two independent reviewers. PEDro scale will be used to systematically appraise methodological quality. Review Manager V.5.4 software will be used for statistical analysis. Weighted mean difference (WMD) or standardized mean difference (SMD) with 95% CI and P-value will be used to calculate treatment effect for each outcome variables.
Results:
Search terms and search databases have been identified. The data extraction sheet has been also developed. This study is expected to be completed by the end of 2022.
Conclusions:
This study will provide an up-to-date evidence on the effectiveness and use of neurodynamic interventions for stroke patients in the clinical practice. Clinical Trial: PROSPERO (International Prospective Register of Systematic Reviews) CRD42022319972
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