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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Nov 12, 2021
Date Accepted: Jan 2, 2022

The final, peer-reviewed published version of this preprint can be found here:

Early Identification of Maternal Cardiovascular Risk Through Sourcing and Preparing Electronic Health Record Data: Machine Learning Study

Shara N, Anderson KM, Falah N, Ahmad MF, Tavazoei D, Hughes JM, Talmadge B, Crovatt S, Dempers R

Early Identification of Maternal Cardiovascular Risk Through Sourcing and Preparing Electronic Health Record Data: Machine Learning Study

JMIR Med Inform 2022;10(2):e34932

DOI: 10.2196/34932

PMID: 35142637

PMCID: 8874927

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

The process of sourcing and preparing electronic health records data to implement a machine-learning algorithm for early identification of maternal cardiovascular risk

  • Nawar Shara; 
  • Kelley M. Anderson; 
  • Noor Falah; 
  • Maryam F. Ahmad; 
  • Darya Tavazoei; 
  • Justin M. Hughes; 
  • Bethany Talmadge; 
  • Samantha Crovatt; 
  • Ramon Dempers

ABSTRACT

Background:

Healthcare data are fragmenting as patients seek care from diverse sources. Consequently, patient care is negatively impacted by disparate health records. Machine learning (ML) offers a disruptive force in its ability to inform and improve patient care and outcomes [6]. However, the differences that exist in each individual’s health records, combined with the lack of health-data standards, in addition to systemic issues that render the data unreliable and that fail to create a single view of each patient, create challenges for ML. While these problems exist throughout healthcare, they are especially prevalent within maternal health, and exacerbate the maternal morbidity and mortality (MMM) crisis in the United States.

Objective:

Maternal patient records were extracted from the electronic health records (EHRs) of a large tertiary healthcare system and made into patient-specific, complete datasets through a systematic method so that a machine-learning-based (ML-based) risk-assessment algorithm could effectively identify maternal cardiovascular risk prior to evidence of diagnosis or intervention within the patient’s record.

Methods:

We outline the effort that was required to define the specifications of the computational systems, the dataset, and access to relevant systems, while ensuring data security, privacy laws, and policies were met. Data acquisition included the concatenation, anonymization, and normalization of health data across multiple EHRs in preparation for its use by a proprietary risk-stratification algorithm designed to establish patient-specific baselines to identify and establish cardiovascular risk based on deviations from the patient’s baselines to inform early interventions.

Results:

Patient records can be made actionable for the goal of effectively employing machine learning (ML), specifically to identify cardiovascular risk in pregnant patients.

Conclusions:

Upon acquiring data, including the concatenation, anonymization, and normalization of said data across multiple EHRs, the use of a machine-learning-based (ML-based) tool can provide early identification of cardiovascular risk in pregnant patients. Clinical Trial: N/A


 Citation

Please cite as:

Shara N, Anderson KM, Falah N, Ahmad MF, Tavazoei D, Hughes JM, Talmadge B, Crovatt S, Dempers R

Early Identification of Maternal Cardiovascular Risk Through Sourcing and Preparing Electronic Health Record Data: Machine Learning Study

JMIR Med Inform 2022;10(2):e34932

DOI: 10.2196/34932

PMID: 35142637

PMCID: 8874927

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