Accepted for/Published in: JMIR Research Protocols
Date Submitted: Sep 24, 2021
Open Peer Review Period: Sep 23, 2021 - Nov 18, 2021
Date Accepted: May 11, 2022
(closed for review but you can still tweet)
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Cardiometabolic and Anthropometric Outcomes of Intermittent Fasting among Overweight and Obese Civil Servants in Malaysia (CAIFA): Study Protocol for A Non-Randomized Controlled Trial
ABSTRACT
Background:
Overweight and obesity among adults is a growing global public health threat and an essential risk factor for various non-communicable diseases. Although intermittent fasting is a generally new dietary approach to weight management that has been increasingly practised worldwide, the effectiveness of two-days per week dry fasting is still unclear.
Objective:
This study aimed to determine the cardiometabolic, anthropometric, dietary intake and quality of life changes among overweight and obese civil servants following combined Intermittent Fasting and Healthy Plate (IFHP) and Healthy Plate (HP), and to explore the participants’ experience.
Methods:
We designed a mixed-method quasi-experimental study that evaluates the effectiveness of IFHP and HP methods among overweight and obese adults. A total of 177 participants were recruited in this study, of which 91 were allocated in the IFHP group and 86 in the HP group. The intervention comprised two phases; supervised (12 weeks) and unsupervised (12 weeks). The data collection was conducted during baseline, after the supervised phase (at week 12), and after the unsupervised phase (at week 24). For each participant, serum and whole blood were collected for analysis. Data on socio-demographic, quality of life, physical activity and dietary intake were also obtained using questionnaires during data collection.
Results:
The majority of the participants were females (n=147, 83.7%) and Malays (n=141, 79.6%). The expected outcomes of this study are changes in body weight, body compositions, quality of life, physical activity, dietary intake and cardiometabolic parameters such as fasting blood glucose, 2-hour post prandial blood glucose, HbA1C, fasting insulin and lipid profile.
Conclusions:
The CAIFA study is a mixed-method study to evaluate the effectiveness of intermittent fasting on cardiometabolic and anthropometric parameters and to explore participants’ experience throughout the study. Clinical Trial: ClinicalTrials.gov NCT05034653
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