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Accepted for/Published in: JMIR Serious Games

Date Submitted: Aug 28, 2021
Date Accepted: Sep 2, 2022

The final, peer-reviewed published version of this preprint can be found here:

Pain Assessment Using Virtual Reality Facemask During Bone Marrow Aspiration: Prospective Study Including Propensity-Matched Analysis

SORET L, Gendron N, Rivet N, Chocron R, macraigne L, Clausse D, Cholley B, Gaussem P, Smadja DM, Darnige L

Pain Assessment Using Virtual Reality Facemask During Bone Marrow Aspiration: Prospective Study Including Propensity-Matched Analysis

JMIR Serious Games 2022;10(4):e33221

DOI: 10.2196/33221

PMID: 36222814

PMCID: 9607885

Pain assessment using virtual reality facemask during bone marrow aspiration: a prospective study including propensity-matched analysis.

  • Lou SORET; 
  • Nicolas Gendron; 
  • Nadia Rivet; 
  • Richard Chocron; 
  • Laure macraigne; 
  • Darless Clausse; 
  • Bernard Cholley; 
  • Pascale Gaussem; 
  • David M Smadja; 
  • Luc Darnige

ABSTRACT

Background:

Bone marrow aspiration (BMA) is a medical procedure necessary to the diagnosis and/or monitoring of patients with hematological or non-hematological disorders. This procedure is considered as painful and patients are generally anxious before and during BMA.

Objective:

This work assessed the effect of immersive virtual reality on pain during BMA.

Methods:

This observational prospective and monocentric study enrolled 105 patients who underwent sternal BMA with lidocaine anesthesia. The study was carried on during two periods. First, virtual reality facemask (VRF) was suggested to all patients in the absence of exclusion criteria. During the second period, BMA were performed without the VRF. For all patients, pain intensity after the procedure was assessed using a 10-point numerical pain rating scale (NPRS). All analysis were performed on propensity score matched cohort (with or without VRF) to evaluate efficacy on NRPS levels.

Results:

Final matched cohort included 12 patients in the VRF group and 24 in control group. No difference in anxiety level before BMA evaluated by the patient himself and by the operator was observed between groups (p=0.71 and 0.42 respectively). No difference of NPRS was observed using VRF when compared to control group (median NPRS 3.8, IQR 2.0–6.3, vs 3.0, IQR 1.9–3.0 respectively, p= 0.09).

Conclusions:

Our study did not prove the efficacy of VRF to reduce pain during BMA.


 Citation

Please cite as:

SORET L, Gendron N, Rivet N, Chocron R, macraigne L, Clausse D, Cholley B, Gaussem P, Smadja DM, Darnige L

Pain Assessment Using Virtual Reality Facemask During Bone Marrow Aspiration: Prospective Study Including Propensity-Matched Analysis

JMIR Serious Games 2022;10(4):e33221

DOI: 10.2196/33221

PMID: 36222814

PMCID: 9607885

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