Accepted for/Published in: JMIR Research Protocols
Date Submitted: Aug 22, 2021
Date Accepted: Dec 8, 2021
Technology-Based Interventions to Promote the HIV PrEP Care Continuum: Protocol for a Systematic Review
ABSTRACT
Background:
Pre-exposure prophylaxis (PrEP) is a promising biomedical prevention method for HIV prevention. Researchers have proposed the PrEP care continuum to guide and evaluate PrEP implementation programs. Technology-based interventions (TBIs) have been widely used in HIV prevention and treatment programs, including promoting the PrEP care continuum. The rapid development of new technology and electronic health methods emphasize the need for a review on the effectiveness of these TBIs.
Objective:
The aim of this systematic review is to summarize the effectiveness and acceptability of TBIs to promote the HIV PrEP care continuum.
Methods:
We will conduct a systematic literature search in PubMed, Embase, Medline, PsycINFO, Web of Science, CINAHL, and the Cochrane Central Register of Controlled Trials following the PRISMA (Preferred Reporting Items for Systematic Reviews and Mate-Analysis) guidelines. Only intervention studies (meeting the criteria of randomized control trials or quasi-experimental studies, etc.) evaluating the effectiveness of TBIs will be included. We will search the National Institutes of Health Research Portfolio Online Reporting Tools (NIH-RePORT) for interventions. PrEP. At least two reviewers will be independently screen and select the studies, extract the data, and evaluate the quality of studies, with discrepancies resolved by a senior author. We will provide a narrative synthesis of included studies and present details about the study populations, descriptions of the interventions, and PrEP related outcomes of significance.
Results:
The protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO, CRD42021249562). As of August 2021, we have completed the initial search and identified 1,213 records. Study screening and data extracting are in process. We expect the results and findings to be finished by December 2021.
Conclusions:
The findings of this review will summarize successful experiences and lessons learned from existing literature and therefore inform the design and implementation of intervention studies for PrEP care promotion.
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