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Accepted for/Published in: JMIR Serious Games

Date Submitted: Jun 4, 2021
Date Accepted: Sep 10, 2021
Date Submitted to PubMed: Dec 6, 2021

The final, peer-reviewed published version of this preprint can be found here:

A Virtual Supermarket Program for the Screening of Mild Cognitive Impairment in Older Adults: Diagnostic Accuracy Study

Chen L, Yan M, Yin H, Meng Q, Wang S, Ding Y, Li G, Wang C

A Virtual Supermarket Program for the Screening of Mild Cognitive Impairment in Older Adults: Diagnostic Accuracy Study

JMIR Serious Games 2021;9(4):e30919

DOI: 10.2196/30919

PMID: 34870610

PMCID: 8686451

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

A Preliminary Study on the Feasibility of Using Virtual Supermarket Program (VSP) Screening for Mild Cognitive Impairment in Older Chinese Adults

  • Li Chen; 
  • Mingli Yan; 
  • Huiru Yin; 
  • Qiuyan Meng; 
  • Shuo Wang; 
  • Yiwen Ding; 
  • Guichen Li; 
  • Chunyan Wang

ABSTRACT

Background:

Virtual reality provides great advantages in screening for mild cognitive impairment (MCI). The Virtual Supermarket Program (VSP) was developed to distinguish MCI from normal cognitive aging in older adults.

Objective:

The objectives were to validate the VSP for differentiating MCI patients and healthy controls (HCs) and for exploring the cutoff scores for different age levels.

Methods:

Subjects were recruited from several nursing homes and communities in Changchun, China. They were divided into an HC group (N = 64) and an MCI group (N = 62). All subjects were administered the VSP and a series of neuropsychological scales. The study included determination of the optimal cutoff, discriminant validity, concurrent validity and test-retest reliability of the VSP. We used the area under the curve (AUC) of the receiver operating characteristic curve to evaluate the discriminant validity and obtain the optimal cutoff. Pearson correlation analysis and the intraclass correlation coefficient were used to evaluate the concurrent validity and test-retest reliability, respectively.

Results:

A cutoff score of 46.4 was optimal for the entire sample, yielding a sensitivity of 85.9% and a specificity of 79.0% for differentiating those with MCI and HCs, and the AUC was 0.870 (95% CI = 0.799 ~ 0.924). There was a moderate positive correlation between VSP total scores and Mini-Mental State Examination scores (r = 0.429, P < .001). There was a strong positive correlation between VSP total scores and Montreal Cognitive Assessment scores (r = 0.645, P < 0.001). The test-retest reliability of the VSP was good (r = 0.588, P = 0.048).

Conclusions:

The self-developed VSP is interesting for participants and reliable and easy for researchers to administer. It has high sensitivity and specificity in the identification of MCI in older Chinese adults, which makes it a promising screening method. Clinical Trial: The study was registered in the Chinese Clinical Trial Registry (registration number: ChiCTR2000040074).


 Citation

Please cite as:

Chen L, Yan M, Yin H, Meng Q, Wang S, Ding Y, Li G, Wang C

A Virtual Supermarket Program for the Screening of Mild Cognitive Impairment in Older Adults: Diagnostic Accuracy Study

JMIR Serious Games 2021;9(4):e30919

DOI: 10.2196/30919

PMID: 34870610

PMCID: 8686451

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