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Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Apr 26, 2021
Date Accepted: Aug 27, 2021

The final, peer-reviewed published version of this preprint can be found here:

mHealth Interventions for Lifestyle and Risk Factor Modification in Coronary Heart Disease: Randomized Controlled Trial

Bae JW, Woo SI, Lee J, Park SD, Kwon SW, Choi SH, Yoon GS, Kim MS, Hwang SS, Lee WK

mHealth Interventions for Lifestyle and Risk Factor Modification in Coronary Heart Disease: Randomized Controlled Trial

JMIR Mhealth Uhealth 2021;9(9):e29928

DOI: 10.2196/29928

PMID: 34559058

PMCID: 8501404

Mobile health interventions for lifestyle and risk factor modification in coronary heart disease: A randomized controlled trial

  • Jang-Whan Bae; 
  • Seoung-Il Woo; 
  • Joongyub Lee; 
  • Sang-Don Park; 
  • Sung Woo Kwon; 
  • Seong Huan Choi; 
  • Gwang-Seok Yoon; 
  • Mi-Sook Kim; 
  • Seung-Sik Hwang; 
  • Won Kyung Lee

ABSTRACT

Background:

The self-management of lifestyle and cardiovascular risk factors is challenging in older patients with coronary heart disease (CHD). Text messaging could be a potential support tool for self-management, but high-quality evidence is lacking.

Objective:

This study aimed to evaluate the effectiveness of a text message program to modify the lifestyle and cardiovascular risk factors in patients who underwent the first percutaneous coronary intervention (PCI).

Methods:

A parallel, single-blinded, 1:1 random allocation clinical trial was conducted on 879 patients treated by PCI, who were recruited during hospital admission from April 2017 to May 2020 in two university hospitals in the Republic of Korea. In addition to standard care, the intervention group received access to a supporting website and four text messages per week for six months regarding a healthy diet, physical activity, smoking, and cardiovascular health. Random allocation at study enrollment and text messaging after hospital discharge was performed automatically using a computer program. The primary outcomes were LDL cholesterol (LDL-C), systolic blood pressure (SBP), and body mass index (BMI). The secondary outcomes were the change in lifestyle and the adherence to the recommended health behaviors.

Results:

Of the eligible population, 440 and 439 patients who underwent PCI were assigned to the intervention and control groups, respectively. A one-way text message program could enhance the physical activity, healthy diet, and medication adherence significantly in patients with CHD (p-value=0.02, <0.01, and <0.04, respectively), so more people were likely to control their cardiovascular risk factors as recommended. The intervention group was more likely to keep all five risk factors as guidelines recommended by 62% (95% CI, 1.05-2.50). On the other hand, it could not reach statistical significance in the physiological measures of the primary outcomes: LDL-C level, SBP, and BMI. Most participants found the text message program to be useful and helpful for motivation to change lifestyle.

Conclusions:

Lifestyle-focused text messages were effective in the self-management of a healthy diet, exercise, and medication adherence, but their influence on physiological measures was modest and limited. Clinical Trial: Clinical Research Information Service (CRiS) at https://cris.nih.go.kr, Identification: KCT0005087


 Citation

Please cite as:

Bae JW, Woo SI, Lee J, Park SD, Kwon SW, Choi SH, Yoon GS, Kim MS, Hwang SS, Lee WK

mHealth Interventions for Lifestyle and Risk Factor Modification in Coronary Heart Disease: Randomized Controlled Trial

JMIR Mhealth Uhealth 2021;9(9):e29928

DOI: 10.2196/29928

PMID: 34559058

PMCID: 8501404

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