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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Apr 13, 2021
Date Accepted: Jul 27, 2021

The final, peer-reviewed published version of this preprint can be found here:

Multiple Sclerosis Progression Discussion Tool Usability and Usefulness in Clinical Practice: Cross-sectional, Web-Based Survey

Ziemssen T, Giovannoni G, Alvarez E, Bhan V, Hersh C, Hoffmann O, Oreja-Guevara C, Robles-Cedeño RR, Trojano M, Vermersch P, Dobay P, Khwaja M, Stadler B, Rauser B, Hach T, Piani-Meier D, Burton J

Multiple Sclerosis Progression Discussion Tool Usability and Usefulness in Clinical Practice: Cross-sectional, Web-Based Survey

J Med Internet Res 2021;23(10):e29558

DOI: 10.2196/29558

PMID: 34612826

PMCID: 8529467

Multiple Sclerosis Progression Discussion Tool: Usability and Usefulness in Clinical Practice

  • Tjalf Ziemssen; 
  • Gavin Giovannoni; 
  • Enrique Alvarez; 
  • Virender Bhan; 
  • Carrie Hersh; 
  • Olaf Hoffmann; 
  • Celia Oreja-Guevara; 
  • Rene R Robles-Cedeño; 
  • Maria Trojano; 
  • Patrick Vermersch; 
  • Pamela Dobay; 
  • Mudeer Khwaja; 
  • Bianca Stadler; 
  • Benedict Rauser; 
  • Thomas Hach; 
  • Daniela Piani-Meier; 
  • Jason Burton

ABSTRACT

Background:

A digital tool (Multiple Sclerosis Progression Discussion tool, MSProDiscuss) was developed to facilitate a discussion between a healthcare professional (HCP) and patient in evaluating early, subtle signs of multiple sclerosis (MS) disease progression.

Objective:

To report findings on the usability and usefulness testing of the MSProDiscuss tool in the real-world clinical setting.

Methods:

In this cross sectional, online survey, HCPs across 34 countries completed an initial individual questionnaire (comprising 7 questions on comprehensibility, usability and usefulness after using MSProDiscuss during each patient consultation) and a final questionnaire (comprising 13 questions on comprehensibility, usability and usefulness, and integration and adoption into clinical practice to capture their overall experience on using the tool). Responses were provided on a 5-point Likert scale. All analyses were descriptive, and no statistical comparisons were made.

Results:

In total, 301 HCPs tested the tool in 6974 MS patients, of which 77% were relapsing remitting MS patients including those suspected to be transitioning to secondary progressive MS. The time taken to complete MSProDiscuss was 1-4 minutes in 97% (initial) to 98% (final) of the cases. In 94% (initial) to 97% (final) cases, HCPs agreed (4 or 5 on the Likert scale) that patients were able to comprehend the questions from the tool. HCPs were willing to use the tool again in the same patient 91% (initial) of the cases. MSProDiscuss was useful in discussing MS symptoms and their impact on daily activities (88% initial and 92% final) and cognitive function (79% for both initial and final) and in discussing progression in general (88% initial and 90% final). While completing the final questionnaire, 95% of HCPs agreed that the questions were similar to those asked in regular consultation and the tool helped to better understand the impact of MS symptoms on daily activities (91%) and cognitive function (80%). Overall, 92% of the HCPs would recommend MSProDiscuss to a colleague, and 86% are willing to integrate it into their clinical practice.

Conclusions:

MSProDiscuss is a usable and useful tool to facilitate a physician-patient discussion on disease progression in daily clinical practice. Most HCPs agreed that the tool is easy to use and were willing to integrate MSProDiscuss into their daily clinical practice.


 Citation

Please cite as:

Ziemssen T, Giovannoni G, Alvarez E, Bhan V, Hersh C, Hoffmann O, Oreja-Guevara C, Robles-Cedeño RR, Trojano M, Vermersch P, Dobay P, Khwaja M, Stadler B, Rauser B, Hach T, Piani-Meier D, Burton J

Multiple Sclerosis Progression Discussion Tool Usability and Usefulness in Clinical Practice: Cross-sectional, Web-Based Survey

J Med Internet Res 2021;23(10):e29558

DOI: 10.2196/29558

PMID: 34612826

PMCID: 8529467

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