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Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Feb 22, 2021
Date Accepted: Jun 25, 2021

The final, peer-reviewed published version of this preprint can be found here:

Smartphone-Assisted High-Intensity Interval Training in Inflammatory Rheumatic Disease Patients: Randomized Controlled Trial

Haglo H, Wang E, Berg OK, Hoff J, Helgerud J

Smartphone-Assisted High-Intensity Interval Training in Inflammatory Rheumatic Disease Patients: Randomized Controlled Trial

JMIR Mhealth Uhealth 2021;9(10):e28124

DOI: 10.2196/28124

PMID: 34673536

PMCID: 8569541

Smartphone assisted high-intensity interval training in inflammatory rheumatic disease patients: A randomized trial - treatment by man or machine?

  • Håvard Haglo; 
  • Eivind Wang; 
  • Ole Kristian Berg; 
  • Jan Hoff; 
  • Jan Helgerud

ABSTRACT

Background:

High-intensity interval training (HIIT) is documented to counteract the reduced maximal oxygen uptake (V̇O2max) and poor cardiovascular health associated with inflammatory rheumatic disease (IRD). However, supervised HIIT is resource demanding.

Objective:

This study sought to investigate if guidance by a smartphone application (APP: Myworkout GO) could yield similar HIIT-induced effects as supervision by healthcare professionals.

Methods:

Forty patients (33 females, 48±12 years; 7 males, 52±11 years), diagnosed with rheumatoid arthritis, spondyloarthritis or systemic lupus erythematosus were randomized to a supervised group (SG) or an APP group (AG). Both groups were instructed to perform 4x4 minute intervals with an intensity corresponding to 85-95% of HRmax twice a week for 10 weeks. Treadmill V̇O2max and health-related quality-of-life (HRQoL), measured using RAND-36, were assessed before and after the exercise period.

Results:

V̇O2max increased (P<.001) in both groups, revealing 3.6±1.3 (SG) and 3.7±1.5 mL·kg-1·min-1 (AG) improvements, with no between-group differences apparent. Improvements in the following HRQoL dimensions; bodily pain, vitality, social functioning and emotional wellbeing were observed for both groups (all P <.001–.05). Again, with no between-group differences detected.

Conclusions:

High-intensity 4x4 minute interval training increased V̇O2max and HRQoL, contributing to the patients´ reduced cardiovascular disease risk, improved health, performance, and enhanced quality of life. Similar improvements were observed if IRD patients were guided by healthcare professionals or an APP, suggesting that utilization of the APP may be excellent in reducing the costs of HIIT as a treatment strategy in this patient population. Clinical Trial: ClinicalTrials.gov, NCT04649528.


 Citation

Please cite as:

Haglo H, Wang E, Berg OK, Hoff J, Helgerud J

Smartphone-Assisted High-Intensity Interval Training in Inflammatory Rheumatic Disease Patients: Randomized Controlled Trial

JMIR Mhealth Uhealth 2021;9(10):e28124

DOI: 10.2196/28124

PMID: 34673536

PMCID: 8569541

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