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Accepted for/Published in: JMIR Formative Research

Date Submitted: Feb 16, 2021
Date Accepted: May 31, 2021
Date Submitted to PubMed: Jun 11, 2021

The final, peer-reviewed published version of this preprint can be found here:

Clinical Utility and Functionality of an Artificial Intelligence–Based App to Predict Mortality in COVID-19: Mixed Methods Analysis

Abdulaal A, Patel A, Al-Hindawi A, Charani E, Alqahtani SA, Davies GW, Mughal N, Moore LSP

Clinical Utility and Functionality of an Artificial Intelligence–Based App to Predict Mortality in COVID-19: Mixed Methods Analysis

JMIR Form Res 2021;5(7):e27992

DOI: 10.2196/27992

PMID: 34115603

PMCID: 8320734

Clinical utility and functionality of an artificial intelligence application to predict mortality in COVID-19: a mixed methods analysis.

  • Ahmed Abdulaal; 
  • Aatish Patel; 
  • Ahmed Al-Hindawi; 
  • Esmita Charani; 
  • Saleh A Alqahtani; 
  • Gary W Davies; 
  • Nabeela Mughal; 
  • Luke Stephen Prockter Moore

ABSTRACT

Background:

Artificial neural networks (ANN) are an increasingly important tool in the context of solving complex medical classification problems. However, one of the principal challenges in leveraging AI technology in the healthcare setting has been the relative inability to translate complex models into clinician workflow at the point of care, in a time-efficient manner for end-users.

Objective:

Here we delineate the development of a COVID-19 outcome prediction application which utilises an ANN and assess its usability in the clinical setting.

Methods:

Usability assessment was conducted on the application using clinical vignettes followed by a semi-structured end-user interview. Usability was specified by effectiveness, efficiency, and satisfaction measures, reported with descriptive statistics. End-user interview data were analysed using a thematic framework, developing themes from the interview narratives.

Results:

Thirty-one Nation Health Service (NHS) physicians at a London teaching hospital, ranging from first year post-graduate through to consultants (post-graduate year 20+). All participants were able to complete the assessment, with a mean time for each patient vignettes of 59.35 seconds (standard deviation (SD) = 10.35). Mean system usability scale (SUS) score was 91.94 (SD = 8.54), which corresponds with an adjective rating of “Excellent”. Thematic analysis described positive themes around (i) the intuitive user interface, and (ii) its utility as a clinical predictive tool. A negative theme was identified around (iii) The primary concern related to use of the application in isolation as opposed to in conjunction with other clinical parameters, yet most clinicians felt that the application could positively reinforce or validate their clinical judgement.

Conclusions:

Translating AI technologies into the clinical setting remains an important but challenging task. We demonstrate the effectiveness, efficiency, and system usability of a web application designed to predict COVID-19 patient outcomes from an ANN.


 Citation

Please cite as:

Abdulaal A, Patel A, Al-Hindawi A, Charani E, Alqahtani SA, Davies GW, Mughal N, Moore LSP

Clinical Utility and Functionality of an Artificial Intelligence–Based App to Predict Mortality in COVID-19: Mixed Methods Analysis

JMIR Form Res 2021;5(7):e27992

DOI: 10.2196/27992

PMID: 34115603

PMCID: 8320734

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