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Accepted for/Published in: JMIR Formative Research

Date Submitted: Dec 31, 2020
Date Accepted: Jul 26, 2021

The final, peer-reviewed published version of this preprint can be found here:

A Mobile Health App (WYZ) for Engagement in Care and Antiretroviral Therapy Adherence Among Youth and Young Adults Living With HIV: Single-Arm Pilot Intervention Study

Saberi P, Lisha NE, Erguera XA, Hudes ES, Johnson MO, Ruel T, Neilands TB

A Mobile Health App (WYZ) for Engagement in Care and Antiretroviral Therapy Adherence Among Youth and Young Adults Living With HIV: Single-Arm Pilot Intervention Study

JMIR Form Res 2021;5(8):e26861

DOI: 10.2196/26861

PMID: 34463622

PMCID: 8441610

WYZ: Results of a pilot intervention of a mobile health application for engagement in care and antiretroviral therapy adherence among youth and young adults living with HIV

  • Parya Saberi; 
  • Nadra E. Lisha; 
  • Xavier A. Erguera; 
  • Estie S. Hudes; 
  • Mallory O. Johnson; 
  • Theodore Ruel; 
  • Torsten B. Neilands

ABSTRACT

Background:

Youth are globally recognized as being vulnerable to HIV. Younger age has been correlated with worse health outcomes. Mobile health (mHealth) delivered interventions have the potential to meet youth where they are, using a device they already access.

Objective:

Using pre-defined benchmarks, we sought to evaluate the feasibility and acceptability of WYZ, an mHealth application, for improved engagement in care and antiretroviral therapy (ART) adherence among youth and young adults living with HIV (YLWH). WYZ was designed and developed with input from YLWH using a Human-Centered Design approach and based on the Information, Motivation, Behavioral Skills framework to address common barriers to care and ART adherence among YLWH.

Methods:

We recruited YLWH (18–29 years old) in the San Francisco Bay Area to take part in a six-month pilot trial. Their participation included completing a baseline and exit survey and participating in seven phone check-ins about their use of WYZ.

Results:

YLWH (N= 79) reported high levels of feasibility and acceptability with WYZ use. We met pre-defined benchmarks for recruitment, mean log-ins per week, tracking ART adherence, posting chat topics, and app crashes reported. Ease of app download, install, and set up, as well as comfort with security, privacy, and anonymity were highly rated. Additionally, participants reported high satisfaction for a research project that was remotely conducted. Participants used the app for shorter timeframes compared to the pre-defined benchmarks.

Conclusions:

We noted high feasibility and acceptability with WYZ. Further research to examine the efficacy of WYZ will enable YLWH and their providers to make informed decisions when using, recommending, and prescribing it for improved engagement in HIV care and ART adherence. Clinical Trial: NCT03587857


 Citation

Please cite as:

Saberi P, Lisha NE, Erguera XA, Hudes ES, Johnson MO, Ruel T, Neilands TB

A Mobile Health App (WYZ) for Engagement in Care and Antiretroviral Therapy Adherence Among Youth and Young Adults Living With HIV: Single-Arm Pilot Intervention Study

JMIR Form Res 2021;5(8):e26861

DOI: 10.2196/26861

PMID: 34463622

PMCID: 8441610

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